Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.011G181200.1 |
Family | GT8 |
Protein Properties | Length: 357 Molecular Weight: 40705 Isoelectric Point: 8.9565 |
Chromosome | Chromosome/Scaffold: 11 Start: 42782445 End: 42783515 |
Description | galacturonosyltransferase-like 4 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 67 | 328 | 0 |
NKDDRIHIAMTLDENYLRGTMAAVLSMLQHSTCPENLSFHFLCAHSDVKLVSSIESTFPYLNFKIYRFDSNRVRGKISKSIRQALDQPLNYARIYLADIL PADVKRVLYLDSDLVVVDDIGKLWDVDMEDKVLAAPEYCHANFTVYFNDAFWSDPVLSNTFQGRNPCYFNTGVMVVDVDKWRKGGYTKKVEQWMAFHKKK RIYHLGSLPPFLLVLAGNIKPVDHRWNQHGLGGDNFEGKCRNLHPGPISLLHWSGKGKPWLR |
Full Sequence |
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Protein Sequence Length: 357 Download |
MALWRTLSIP IASPHGLILS FLLLLHSAVT TTVAIRVRTI IHDPSPVKLP VFREAPAFRN 60 GDSCGSNKDD RIHIAMTLDE NYLRGTMAAV LSMLQHSTCP ENLSFHFLCA HSDVKLVSSI 120 ESTFPYLNFK IYRFDSNRVR GKISKSIRQA LDQPLNYARI YLADILPADV KRVLYLDSDL 180 VVVDDIGKLW DVDMEDKVLA APEYCHANFT VYFNDAFWSD PVLSNTFQGR NPCYFNTGVM 240 VVDVDKWRKG GYTKKVEQWM AFHKKKRIYH LGSLPPFLLV LAGNIKPVDH RWNQHGLGGD 300 NFEGKCRNLH PGPISLLHWS GKGKPWLRLD SRKPCVVDHL WAPYDLYRSS RHFLEE* 360 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
PLN02867 | PLN02867 | 3.0e-17 | 155 | 329 | 185 | + Probable galacturonosyltransferase |
cd00505 | Glyco_transf_8 | 1.0e-18 | 72 | 328 | 265 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. |
cd06429 | GT8_like_1 | 1.0e-24 | 72 | 329 | 278 | + GT8_like_1 represents a subfamily of GT8 with unknown function. A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. |
cd04194 | GT8_A4GalT_like | 9.0e-28 | 72 | 326 | 269 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. |
pfam01501 | Glyco_transf_8 | 8.0e-62 | 73 | 330 | 260 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD96888.1 | 0 | 18 | 356 | 10 | 351 | hypothetical protein [Cleome spinosa] |
RefSeq | NP_187277.1 | 0 | 28 | 356 | 22 | 351 | GATL4 (Galacturonosyltransferase-like 4); polygalacturonate 4-alpha-galacturonosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002277334.1 | 0 | 27 | 356 | 24 | 352 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311936.1 | 0 | 39 | 356 | 34 | 347 | glycosyltransferase, CAZy family GT8 [Populus trichocarpa] |
RefSeq | XP_002516817.1 | 0 | 26 | 356 | 24 | 353 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ga8_A | 0.00000003 | 156 | 328 | 83 | 254 | A Chain A, Crystal Structure Of Human Sarcomeric Mitochondrial Creatine Kinase |
PDB | 1g9r_A | 0.00000003 | 156 | 328 | 83 | 254 | A Chain A, Crystal Structure Of Galactosyltransferase Lgtc In Complex With Mn And Udp-2f-Galactose |
PDB | 1ss9_A | 0.00000003 | 156 | 328 | 83 | 254 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
PDB | 3tzt_B | 0.002 | 157 | 249 | 88 | 171 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
PDB | 3tzt_A | 0.002 | 157 | 249 | 88 | 171 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |