Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.012G151700.4 |
Family | GT24 |
Protein Properties | Length: 1554 Molecular Weight: 175245 Isoelectric Point: 6.3862 |
Chromosome | Chromosome/Scaffold: 12 Start: 32540759 End: 32556725 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1333 | 1531 | 0 |
INIFSIASGHLYERFLKIMILSVLKNTHRPVKFWFIKNYLSPQFKDVIPHMAQEYGFDYELVTYKWPTWLHKQTEKQRIIWAYKILFLDVIFPISLEKVI FVDADQVVRADMGDLYDMDIKGRPLAYTPFCDNNKDMDGYRFWRQGFWREHLRGRPYHISALYVVDLVKFRETAAGDNLRVFYESLSKDPNSLANLDQA |
Full Sequence |
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Protein Sequence Length: 1554 Download |
MDTCFRSRFC ILILLTCLLI SGFTFVGAQN RRPKNVQVAI RAKWSGTPLL LEAGELLSKE 60 SKNLFWEFID DWLLVGKTDD DSHSAKDCLV KILKHGSSLL SEQLASLFEF SLTLRSASPR 120 LVLYRQLAEE SLSSFPLSDD SYSHNASGVD DSEAVVTKKL DPLLVGVNPK SPRGKCCWVD 180 VGEELFFEVA ELQSWLLGPN EVNGDSFQQP ELYEFDHIHF DSNIASPVAI LYGALGTECF 240 REFHVTLVQA AKEGKVKYVV RPVLPSGCEG EVGQCGAVGA RDSLNLGGYG VELALKNMEY 300 KAMDDSTVKK GVTLEDPRTE DLSQEVRGFI FSKILERKPD LTSEIMAFRD YLLSSTISDT 360 LDVWELKDLG HQTAQRIVQA SDPLQSMQEI NQNFPSVVSS LSRMKLNDSV KDEIIANQRM 420 IPPGKSLMAL NGALINIEDI DLYLLIDLVH QELSLADQFS KLKLPRSTIR KLLSTMTPPE 480 SDAFRVDFRS DHVHYLNNLE EDAMYRRWRS NINDILMPVF PGQLRYIRKN LFHAVYVLDP 540 STVSGLQSID MITSFYENSF PMRFGVILYS TQFIKKIEQS GGELHSSEHD GELEDDKSSL 600 IIRLFIYIKE NHGIQSAFQF LSNINRLRTE SADSTDEALE MHHIEGAFVE TLLPKAKSPP 660 QEILLKLEKE QSFKELSQES SLFVFKLGVN KLQCCLLMNG LVFDSSEDAL INAMNDELPR 720 IQEQVYYGKI NSHTNVLDKF LSENGVSRYN PQIIAGGKVK PGFVSLASPA LGGESVLNEI 780 NYLHSPGTVD DVKPVTHLLA VDVTSRKGIK LLREAIRYLI QGSKNARVGV LFTAGQDANL 840 SNILLVKTFE ITAASYSHKK KVLEFLDQVC SFYEHKYILR SPAAAESTQA FINKVYELAE 900 ANELPSKTYK SSLSEAYNLK LIEHLNKVAQ YLYRQFGISS GVNAVITNGR ITSLDAGVFL 960 GDDLHLLESV EFNHRIKHIV EIVEEVSWHG IDPDMLTSKY VSDIIMLISS SMATRDRSAE 1020 SARFEILNAQ YSAVILNNEN SSIHIDAVVD PLSPSGQKLS SLLRVLAKYV HPSMRIVLNP 1080 MSSLVDLPLK NYYRYVIPTM EDFSSTDYTV NGPKAFFANM PLSKTLTMNL DVPEPWLVEP 1140 VIAVHDLDNI LLENLGDIRT LQAVFELEAL VLTGHCAEKD RDPPRGLQLI LGTKNTPHLV 1200 DTIVMANLGY WQMKVSPGVW YLQLAPGRSS ELYLFRDGGD YGNQEKSLSK RITINDLRGK 1260 VVHLEVVKKK GKEQEKLLIS SDDDKHSKEK GHNGWNSNLL KWASGFIGGS EKSKKSSDSS 1320 VDHGKGGRHG KTINIFSIAS GHLYERFLKI MILSVLKNTH RPVKFWFIKN YLSPQFKDVI 1380 PHMAQEYGFD YELVTYKWPT WLHKQTEKQR IIWAYKILFL DVIFPISLEK VIFVDADQVV 1440 RADMGDLYDM DIKGRPLAYT PFCDNNKDMD GYRFWRQGFW REHLRGRPYH ISALYVVDLV 1500 KFRETAAGDN LRVFYESLSK DPNSLANLDQ ARSSKLRSTH STNLFITPRM AMV* 1560 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06429 | GT8_like_1 | 0.0003 | 1356 | 1455 | 106 | + GT8_like_1 represents a subfamily of GT8 with unknown function. A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. | ||
cd04194 | GT8_A4GalT_like | 9.0e-12 | 1333 | 1530 | 206 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 1.0e-42 | 1333 | 1530 | 199 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 5.0e-80 | 1002 | 1207 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 2.0e-133 | 1333 | 1530 | 198 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 1 | 1531 | 1 | 1542 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
EMBL | CBI23772.1 | 0 | 1 | 1321 | 1 | 1301 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_177278.3 | 0 | 1 | 1549 | 1 | 1515 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 1 | 1549 | 1 | 1518 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 1 | 1543 | 1 | 1512 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |