Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.013G193600.1 |
Family | GT47 |
Protein Properties | Length: 475 Molecular Weight: 54403.4 Isoelectric Point: 8.2165 |
Chromosome | Chromosome/Scaffold: 13 Start: 49491618 End: 49494481 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 142 | 418 | 0 |
KSLKIYVYPHSKDDPFANVLLPPDTDCKGNYASELMFKKALMESHFVTKDPNEAHLFYMPFSISSMRSDPRIDVHGIPDFVQNYISNITLKYPYWNRTGG ADHFYVACHSIGKIAFKKAFVARLNVIQLVCSSTYFPSSYLPHKDASLPQVWPRGGDPPNLLTSQRKRLAFFAGAVNSPVRIALLKVWENDTEIFAHFGR LNTPYYEQFLGSKFCIHVKGFEVNTARVADALFYGCVPIILANHYDLPFTDILNWKSFSVVVHHIDIPVLKKILQGI |
Full Sequence |
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Protein Sequence Length: 475 Download |
MGQSSSLVYQ IFQHRFPATF KGFFYFLPIS LALTTLLLIF IYISTTANVT KTHSQTTLYL 60 QTLPSLINNI DQTSNLPIVP FEDNEDDNDN LFADPSRTAR LSRASQWLLG NIFGLIDGND 120 TNNKEAYHDG DIFLQDYKQM NKSLKIYVYP HSKDDPFANV LLPPDTDCKG NYASELMFKK 180 ALMESHFVTK DPNEAHLFYM PFSISSMRSD PRIDVHGIPD FVQNYISNIT LKYPYWNRTG 240 GADHFYVACH SIGKIAFKKA FVARLNVIQL VCSSTYFPSS YLPHKDASLP QVWPRGGDPP 300 NLLTSQRKRL AFFAGAVNSP VRIALLKVWE NDTEIFAHFG RLNTPYYEQF LGSKFCIHVK 360 GFEVNTARVA DALFYGCVPI ILANHYDLPF TDILNWKSFS VVVHHIDIPV LKKILQGISN 420 EEFAMLQSNA LRVRKHFQWH TPPIDFDAFH MSMYELWKRR GVVRVRLTPS MEFM* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-61 | 140 | 418 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 123 | 470 | 138 | 486 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 95 | 467 | 80 | 447 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 95 | 472 | 80 | 450 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 140 | 470 | 1 | 327 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 140 | 465 | 1 | 326 | catalytic, putative [Ricinus communis] |