Basic Information | |
---|---|
Species | Gossypium raimondii |
Cazyme ID | Gorai.013G219000.2 |
Family | GT47 |
Protein Properties | Length: 783 Molecular Weight: 88395.9 Isoelectric Point: 6.6675 |
Chromosome | Chromosome/Scaffold: 13 Start: 53881643 End: 53885334 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 452 | 733 | 0 |
NTLKVYVYKEGKRPIVHTPVLRGIYASEGWFMKQLESNKKFVTKNPRDAHLFYLPFSSRMLEETLYVPDSHSHKNLIEYLKNYVDTIAAKYPFWNRTEGA DHFLVACHDWAPSETRNHMANCIRALCNSDVREGYVFGKDVSLPETYVRNPQKPLRDLGGNPPSKRPILAFFAGSMHGYLRPILLEQWGNKDPDMKIFGK MPNVKGKMNYIRHMKSSKYCLCPRGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLNWESFSVFILEKDIPNLKKILLSI |
Full Sequence |
---|
Protein Sequence Length: 783 Download |
MGHELKSLSQ LDTRKLIWLI GITFAVIVTF QYIELPYGNV LWSLFPSGKV SVDEKSSFLA 60 SGPSSAESGF YFNGTNAGNE TVHDDEIFEG KDIDTDVITE ADVGLNKSST FGEGTKAWKE 120 SSTAEPVELN KNSTVDNAGN ETAHDDEIFE GRDIDTDIIT EADVGLNKSS TFNEGTKAPK 180 ESSTAELVLE LNKNSTVNNA ESSKSEEFEK DSNITSLNNL NQTGAVNETA KADDFTPEVG 240 LNRSSILDKE LDERSNITML NIAESSNNKS VAENVGTSEE SFASKNDTVD INTSNNNAPD 300 TGLGTTNSTS EKGVKTNISA PVVSFNSSIS SVEQHVTPSF DKNEKPKPKP IQNDFTKPSD 360 NSSPRKAPKL KKKPEMLPPA VTTIADMNNL LYQSRVSYES PTPKWSSRAD KVLLEARLQI 420 ENAPIIKNDP QLYAPLFRNL SMFKRSYELM ENTLKVYVYK EGKRPIVHTP VLRGIYASEG 480 WFMKQLESNK KFVTKNPRDA HLFYLPFSSR MLEETLYVPD SHSHKNLIEY LKNYVDTIAA 540 KYPFWNRTEG ADHFLVACHD WAPSETRNHM ANCIRALCNS DVREGYVFGK DVSLPETYVR 600 NPQKPLRDLG GNPPSKRPIL AFFAGSMHGY LRPILLEQWG NKDPDMKIFG KMPNVKGKMN 660 YIRHMKSSKY CLCPRGYEVN SPRVVEAIFY ECVPVIISDN FVPPFFEVLN WESFSVFILE 720 KDIPNLKKIL LSIPIKRYRQ MQLRVKKIQQ HFLWHPKPEK YDIFHMILHS VWYNRVFQMK 780 PR* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-76 | 454 | 733 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 359 | 779 | 172 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0.0000000002 | 1 | 143 | 1 | 142 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 191 | 782 | 64 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 320 | 782 | 9 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 387 | 782 | 1 | 398 | predicted protein [Populus trichocarpa] |