| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os01g71300.1 |
| Family | CE1 |
| Protein Properties | Length: 293 Molecular Weight: 32181.6 Isoelectric Point: 7.88 |
| Chromosome | Chromosome/Scaffold: 1 Start: 41251226 End: 41272319 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 34 | 286 | 0 |
| SATLGCPMTFSVFLPPSPASDLPVLYWLSGLTCNDENFVTKAGAQRAAAAHGIALVAPDTSPRGLNIEGEADSWDFGVGAGFYLNATNEKWKNWRMYDYV VKELPKVLSDNFEQLNTSRASIFGHSMGGHGALTIYLKNTDKYKSVSAFSPVVNPINCPWGQKAFSNYLGPAKSDWKEYDATCLIKKCNKISTPILIDQG EDDKFLAKQLLPRNFEEACKAVGAPLTLRMQPGYDHSYFFIATFIDDHIAHHS | |||
| Full Sequence |
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| Protein Sequence Length: 293 Download |
| MAAAAPSPPP VAALEQMSRT KMFGGHNLRF RHHSATLGCP MTFSVFLPPS PASDLPVLYW 60 LSGLTCNDEN FVTKAGAQRA AAAHGIALVA PDTSPRGLNI EGEADSWDFG VGAGFYLNAT 120 NEKWKNWRMY DYVVKELPKV LSDNFEQLNT SRASIFGHSM GGHGALTIYL KNTDKYKSVS 180 AFSPVVNPIN CPWGQKAFSN YLGPAKSDWK EYDATCLIKK CNKISTPILI DQGEDDKFLA 240 KQLLPRNFEE ACKAVGAPLT LRMQPGYDHS YFFIATFIDD HIAHHSQFLK SA* 300 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1506 | DAP2 | 0.0003 | 89 | 285 | 219 | + Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism] | ||
| pfam00756 | Esterase | 3.0e-50 | 34 | 284 | 264 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 7.0e-85 | 14 | 292 | 310 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 4.0e-128 | 15 | 289 | 277 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 14 | 291 | 279 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0005576 | extracellular region |
| GO:0006508 | proteolysis |
| GO:0008150 | biological_process |
| GO:0008152 | metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 16 | 290 | 7 | 283 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| RefSeq | NP_001045351.1 | 0 | 1 | 292 | 1 | 292 | Os01g0939700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001148438.1 | 0 | 5 | 292 | 2 | 290 | esterase D [Zea mays] |
| RefSeq | XP_002284489.1 | 0 | 16 | 289 | 7 | 282 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002456916.1 | 0 | 12 | 292 | 3 | 284 | hypothetical protein SORBIDRAFT_03g045400 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 13 | 291 | 2 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 13 | 291 | 2 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 13 | 291 | 3 | 280 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 13 | 291 | 3 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 13 | 291 | 3 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CT848008 | 280 | 14 | 293 | 0 |
| EG384989 | 280 | 14 | 293 | 0 |
| CJ684473 | 272 | 22 | 293 | 0 |
| FF349243 | 273 | 14 | 286 | 0 |
| CO446000 | 267 | 19 | 284 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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