| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os01g71300.2 |
| Family | CE1 |
| Protein Properties | Length: 245 Molecular Weight: 27123.8 Isoelectric Point: 7.4966 |
| Chromosome | Chromosome/Scaffold: 1 Start: 41251226 End: 41272319 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE1 | 7 | 238 | 0 |
| AQVLYWLSGLTCNDENFVTKAGAQRAAAAHGIALVAPDTSPRGLNIEGEADSWDFGVGAGFYLNATNEKWKNWRMYDYVVKELPKVLSDNFEQLNTSRAS IFGHSMGGHGALTIYLKNTDKYKSVSAFSPVVNPINCPWGQKAFSNYLGPAKSDWKEYDATCLIKKCNKISTPILIDQGEDDKFLAKQLLPRNFEEACKA VGAPLTLRMQPGYDHSYFFIATFIDDHIAHHS | |||
| Full Sequence |
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| Protein Sequence Length: 245 Download |
| MLPRGCAQVL YWLSGLTCND ENFVTKAGAQ RAAAAHGIAL VAPDTSPRGL NIEGEADSWD 60 FGVGAGFYLN ATNEKWKNWR MYDYVVKELP KVLSDNFEQL NTSRASIFGH SMGGHGALTI 120 YLKNTDKYKS VSAFSPVVNP INCPWGQKAF SNYLGPAKSD WKEYDATCLI KKCNKISTPI 180 LIDQGEDDKF LAKQLLPRNF EEACKAVGAP LTLRMQPGYD HSYFFIATFI DDHIAHHSQF 240 LKSA* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12697 | Abhydrolase_6 | 0.0002 | 98 | 225 | 128 | + Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity. | ||
| pfam00756 | Esterase | 3.0e-42 | 9 | 236 | 240 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 1.0e-74 | 9 | 244 | 261 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-113 | 4 | 241 | 239 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 1.0e-173 | 9 | 243 | 235 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0005576 | extracellular region |
| GO:0006508 | proteolysis |
| GO:0008150 | biological_process |
| GO:0008152 | metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001045351.1 | 0 | 9 | 244 | 57 | 292 | Os01g0939700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001148438.1 | 0 | 3 | 244 | 48 | 290 | esterase D [Zea mays] |
| RefSeq | XP_002284489.1 | 0 | 9 | 241 | 50 | 282 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002456916.1 | 0 | 3 | 244 | 42 | 284 | hypothetical protein SORBIDRAFT_03g045400 [Sorghum bicolor] |
| RefSeq | XP_002523655.1 | 0 | 9 | 241 | 20 | 253 | Esterase D, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 5 | 243 | 43 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 5 | 243 | 43 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 9 | 243 | 49 | 280 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 9 | 243 | 49 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 9 | 243 | 49 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CT848008 | 237 | 9 | 245 | 0 |
| CJ684473 | 237 | 9 | 245 | 0 |
| EG384989 | 237 | 9 | 245 | 0 |
| HX134911 | 233 | 13 | 245 | 0 |
| BJ231425 | 231 | 15 | 245 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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