| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os03g05060.1 |
| Family | GT47 |
| Protein Properties | Length: 505 Molecular Weight: 57048.2 Isoelectric Point: 9.7842 |
| Chromosome | Chromosome/Scaffold: 3 Start: 2466458 End: 2468340 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 85 | 429 | 0 |
| CRGRYIYVHDLPRRFNDDILRDCRKTRDHWPDMCGFVSNAGLGRPLVDRADGVLTGEAGWYGTHQFALDAIFHNRMKQYECLTNQSAVADAVFVPFYAGF DFVRYHWGYDNATRDAASVDLTQWLMRRPEWRRMGGRDHFLVAGRTGWDFRRDTNINPNWGTNLLVMPGGRDMSVLVLESSLLNGSDYAVPYPTYFHPRS DADVFRWQDRVRGMQRRWLMAFVGAPRPDDPKNIRAQIIAQCNATSACSQLGCAFGSSQCHSPGNIMRLFQKATFCLQPPGDSYTRRSVFDSMVAGCIPV FFHNATAYLQYAWHLPREHAKYSVFISEHDVRAGNVSIEATLRAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 505 Download |
| MRFSVVISSW ILNRQLIKSA PKGGGRQQRR AKGMEKVAVG LLPPLRFIAV LAVVSWTSFI 60 YCHFSLLSGG LLLGHGGGDD GADPCRGRYI YVHDLPRRFN DDILRDCRKT RDHWPDMCGF 120 VSNAGLGRPL VDRADGVLTG EAGWYGTHQF ALDAIFHNRM KQYECLTNQS AVADAVFVPF 180 YAGFDFVRYH WGYDNATRDA ASVDLTQWLM RRPEWRRMGG RDHFLVAGRT GWDFRRDTNI 240 NPNWGTNLLV MPGGRDMSVL VLESSLLNGS DYAVPYPTYF HPRSDADVFR WQDRVRGMQR 300 RWLMAFVGAP RPDDPKNIRA QIIAQCNATS ACSQLGCAFG SSQCHSPGNI MRLFQKATFC 360 LQPPGDSYTR RSVFDSMVAG CIPVFFHNAT AYLQYAWHLP REHAKYSVFI SEHDVRAGNV 420 SIEATLRAIP AATVERMREE VIRLIPSVIY ADPRSKLETV RDAFDVAVEG IIDRIAMTRG 480 GYARSWLRPK QSRQALDARR RRLS* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-67 | 84 | 429 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005794 | Golgi apparatus |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007165 | signal transduction |
| GO:0008152 | metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAO17347.1 | 0 | 15 | 504 | 159 | 648 | Hypothetical protein [Oryza sativa Japonica Group] |
| GenBank | EEC74505.1 | 0 | 16 | 504 | 194 | 682 | hypothetical protein OsI_09985 [Oryza sativa Indica Group] |
| GenBank | EEE58313.1 | 0 | 15 | 504 | 193 | 682 | hypothetical protein OsJ_09380 [Oryza sativa Japonica Group] |
| RefSeq | NP_001048943.1 | 0 | 1 | 504 | 1 | 504 | Os03g0144300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002468519.1 | 0 | 34 | 481 | 1 | 452 | hypothetical protein SORBIDRAFT_01g047290 [Sorghum bicolor] |
