| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os04g47280.1 |
| Family | GH29 |
| Protein Properties | Length: 518 Molecular Weight: 56792.3 Isoelectric Point: 4.5648 |
| Chromosome | Chromosome/Scaffold: 4 Start: 28071433 End: 28074595 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 44 | 339 | 0 |
| QLQWQLSEMALFLHFGPNTFTDSEWGSVRADPAVFAPSALDAGQWARAAAAGGFGRVVLTAKHHDGFCLWPSALTNYSVAASPWKGGAGDVVGELAAAAR AEGIGLGLYLSPWDRHEPVYGDTVAYNEHYLGQMTELLTRYGDVEEVWLDGAKGEGKDMDYMFDAWFALIHQLQQRVVIFSDAGPDTRWVGDEAGVAGYT CWSPFNKSTVTIGHIIPEYSRCGDPFGQDWVPAECDVSIRPGWFWHASEKPKNATTLLDIYYKSVGRNCLLILNVPPNSSGLISTEDMQVLQEFTE | |||
| Full Sequence |
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| Protein Sequence Length: 518 Download |
| MATILLLLLG LLVGLPLLRA HGVTGSAAPT PPPLPVLPVP SYAQLQWQLS EMALFLHFGP 60 NTFTDSEWGS VRADPAVFAP SALDAGQWAR AAAAGGFGRV VLTAKHHDGF CLWPSALTNY 120 SVAASPWKGG AGDVVGELAA AARAEGIGLG LYLSPWDRHE PVYGDTVAYN EHYLGQMTEL 180 LTRYGDVEEV WLDGAKGEGK DMDYMFDAWF ALIHQLQQRV VIFSDAGPDT RWVGDEAGVA 240 GYTCWSPFNK STVTIGHIIP EYSRCGDPFG QDWVPAECDV SIRPGWFWHA SEKPKNATTL 300 LDIYYKSVGR NCLLILNVPP NSSGLISTED MQVLQEFTEI RQTIFSQNFA ANATVTASTV 360 RGGLGNQQFA PSNVLQESIY SYWAPEEGQS SWEMLFDLGQ SASFNVIQLQ EPIQMGQRVI 420 KFRVEILVDE LWQTIVEGTT IGYKRLFQFP VVEGQFLKLS IDGARADPLI SFFGVFTDSF 480 SVTYSLENHE KPSVVNSSEV IMLRTDHSFG NKSIATM* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 6.0e-29 | 100 | 339 | 266 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 4.0e-29 | 100 | 339 | 257 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 6.0e-59 | 44 | 476 | 444 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005515 | protein binding |
| GO:0005773 | vacuole |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG47369.1 | 0 | 21 | 517 | 17 | 513 | alpha-L-fucosidase 1 precursor [Zea mays] |
| EMBL | CAH68057.1 | 0 | 1 | 517 | 1 | 517 | B0103C08-B0602B01.14 [Oryza sativa (indica cultivar-group)] |
| RefSeq | NP_001053546.1 | 0 | 1 | 517 | 1 | 517 | Os04g0560400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001131532.1 | 0 | 21 | 517 | 17 | 513 | hypothetical protein LOC100192871 [Zea mays] |
| RefSeq | XP_002448322.1 | 0 | 21 | 517 | 17 | 513 | hypothetical protein SORBIDRAFT_06g025200 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3mo4_B | 0 | 40 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 40 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 40 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 40 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3uet_B | 0 | 40 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
