| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os04g48400.1 |
| Family | AA3 |
| Protein Properties | Length: 592 Molecular Weight: 63981.2 Isoelectric Point: 6.3834 |
| Chromosome | Chromosome/Scaffold: 4 Start: 28870310 End: 28872728 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 46 | 579 | 0 |
| VSYYDYIIVGGGTAGCPLAATLSQRFRVLLLERGGSPYDDERIGNMTRFADTLSDTSPSSPAQRFVSEDGVINSRPRVLGGGSCINAGFYTRASDEYVRG LGWDLEATTAAYRWVEDVVAFQPELGPWQSALERGLLEAGIAPQNGFTFDHLGGTKVGGSIFDAEGRRHTAADLLRYARTDGIDVLLRARVAKILFNVRA GRRPVAHGVVFHDSEGQMHRAYLSNGRGNEIILSAGAMGSPQLLMLSGVGPADHLRSFGITLVLNQPAVGQGMSDNPMNAIYVPSPSPVEVSLIQVVGIT EVGSYIEGASGANWGVRRSGSGGDRPHRNFGMFSPQTGQLATVPPKQRTPEAIARAAEAMSQLDDTAFRGGFILEKILGPLSTGHLELRNRNPDDNPSVT FNYFAHPEDLRRCVAGVSVIERVIRSEAFANFTYPYFSVETLLNMTAGFPVNLRPRHDNDSTSLEQFCKDTVMTIWHYHGGCQVNRVVDAEYRVIGVDAL RVIDGSTFNASPGTNPQATVMMLGRYMGVKIQNE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 592 Download |
| MASDMDTTRA LAILAATSFV AMLACVQAAG DESYTFMKDA VQSPQVSYYD YIIVGGGTAG 60 CPLAATLSQR FRVLLLERGG SPYDDERIGN MTRFADTLSD TSPSSPAQRF VSEDGVINSR 120 PRVLGGGSCI NAGFYTRASD EYVRGLGWDL EATTAAYRWV EDVVAFQPEL GPWQSALERG 180 LLEAGIAPQN GFTFDHLGGT KVGGSIFDAE GRRHTAADLL RYARTDGIDV LLRARVAKIL 240 FNVRAGRRPV AHGVVFHDSE GQMHRAYLSN GRGNEIILSA GAMGSPQLLM LSGVGPADHL 300 RSFGITLVLN QPAVGQGMSD NPMNAIYVPS PSPVEVSLIQ VVGITEVGSY IEGASGANWG 360 VRRSGSGGDR PHRNFGMFSP QTGQLATVPP KQRTPEAIAR AAEAMSQLDD TAFRGGFILE 420 KILGPLSTGH LELRNRNPDD NPSVTFNYFA HPEDLRRCVA GVSVIERVIR SEAFANFTYP 480 YFSVETLLNM TAGFPVNLRP RHDNDSTSLE QFCKDTVMTI WHYHGGCQVN RVVDAEYRVI 540 GVDALRVIDG STFNASPGTN PQATVMMLGR YMGVKIQNER LGNEGLGRRN L* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 2.0e-29 | 49 | 320 | 314 | + choline dehydrogenase; Validated | ||
| TIGR03970 | Rv0697 | 8.0e-33 | 50 | 569 | 560 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 8.0e-39 | 50 | 586 | 579 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 8.0e-47 | 49 | 570 | 568 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 34 | 584 | 562 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005488 | binding |
| GO:0005623 | cell |
| GO:0008152 | metabolic process |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY87068.1 | 0 | 11 | 587 | 1 | 580 | hypothetical protein OsI_08464 [Oryza sativa Indica Group] |
| RefSeq | NP_001053612.1 | 0 | 1 | 591 | 1 | 591 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001146691.1 | 0 | 11 | 586 | 10 | 594 | hypothetical protein LOC100280292 [Zea mays] |
| RefSeq | XP_002446965.1 | 0 | 2 | 586 | 3 | 590 | hypothetical protein SORBIDRAFT_06g025960 [Sorghum bicolor] |
| RefSeq | XP_002454481.1 | 0 | 1 | 581 | 1 | 580 | hypothetical protein SORBIDRAFT_04g031910 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 31 | 580 | 8 | 517 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
| PDB | 3gdp_A | 0 | 31 | 580 | 8 | 517 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
| PDB | 3gdn_B | 0 | 31 | 580 | 8 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 31 | 580 | 8 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 31 | 580 | 8 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
| cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
| suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
