| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os06g07887.1 |
| Family | GT47 |
| Protein Properties | Length: 442 Molecular Weight: 48793.9 Isoelectric Point: 9.4219 |
| Chromosome | Chromosome/Scaffold: 6 Start: 3872355 End: 3874569 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 205 | 391 | 0 |
| SRGHPELYANAIRALCNANTSEGFRPDKDVSIPEINLYDGDMPPELLSPAPPPPRPFLAFFAGGRHGHVRDLLLRHWKGRDPAVFPVYEYDLPSIPVSVS GDGDTDAGGEGGNPYYWYMRRSRFCLCPSGHEVASPRVVEAIHAGCVPVVVADGYAPPFADVLRWEAFSVAVAVADVPRLRELLERI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 442 Download |
| MAPRLSVKKC LIILALAAAA AIAGFLSVAG AGRGRSSSSS PARRLSNGLA AERARMAMAR 60 AASPTVEREL DAARAAIRRA ARRRRHGDLA GGEGRSSSNV SSAKWLSFFG DADHARLERV 120 YRNPAAFYRS YVEMERRFKV YVYEEGEPPI AHEGPCKNIY AVEGRFIEEL ELMAPPLGGV 180 RTWDPARAHA LFLPLSVSQM GPHASRGHPE LYANAIRALC NANTSEGFRP DKDVSIPEIN 240 LYDGDMPPEL LSPAPPPPRP FLAFFAGGRH GHVRDLLLRH WKGRDPAVFP VYEYDLPSIP 300 VSVSGDGDTD AGGEGGNPYY WYMRRSRFCL CPSGHEVASP RVVEAIHAGC VPVVVADGYA 360 PPFADVLRWE AFSVAVAVAD VPRLRELLER IPAPEVERLR DGVRLVKRHF MLHQPPERLD 420 MFHMILHSVW LRRLNLRLNS H* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-33 | 134 | 391 | 315 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD44815.1 | 0 | 200 | 441 | 273 | 514 | putative pectin-glucuronyltransferase [Oryza sativa Japonica Group] |
| EMBL | CAH67778.1 | 0 | 62 | 439 | 35 | 440 | H0201G08.5 [Oryza sativa (indica cultivar-group)] |
| GenBank | EEE65199.1 | 0 | 1 | 200 | 1 | 203 | hypothetical protein OsJ_20321 [Oryza sativa Japonica Group] |
| GenBank | EEE65199.1 | 0 | 200 | 441 | 310 | 551 | hypothetical protein OsJ_20321 [Oryza sativa Japonica Group] |
| RefSeq | NP_001052025.1 | 0 | 99 | 439 | 64 | 440 | Os04g0109900 [Oryza sativa (japonica cultivar-group)] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
