| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os08g34020.2 |
| Family | GT47 |
| Protein Properties | Length: 515 Molecular Weight: 56923.7 Isoelectric Point: 9.7622 |
| Chromosome | Chromosome/Scaffold: 8 Start: 21314563 End: 21317684 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 127 | 452 | 0 |
| LRVYLYDLPPEFHFGMLGWDGKAAGAAWPDVAGDPRAVPRYPGGLNLQHSVEYWLTLDILSSTTSGDHRRRRPCTAVRVTNASLADVFLVPFFASLSYNR QSKSPHGGHGSGGRSDRQLQGELVRYLARREEWRRWGGADHLVVPHHPNSMMDARRRLSAAMFVLSDFGRYPPDVANLRKDVIAPYKHVVPSLGDGDSPG FEQRPVLAYFQGAIHRKNGGRVRQRLYQLIKDEKDVHFTYGSVRQNGIRRATKGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDDIELPFEDVLD YSAFCVFVRASDAVKRGFLLHLLRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 515 Download |
| MVAERKMQPS PAAPPAAEHR RRALLRYVVF LAVSLLAFSC WALVSSRIDG AVLAATAGGE 60 HDDHDGIIVR SSTQAEMPAR GGNATSRGAV EVGVGTPAAM ITRQPSSGET TTTAALAATC 120 DAESALLRVY LYDLPPEFHF GMLGWDGKAA GAAWPDVAGD PRAVPRYPGG LNLQHSVEYW 180 LTLDILSSTT SGDHRRRRPC TAVRVTNASL ADVFLVPFFA SLSYNRQSKS PHGGHGSGGR 240 SDRQLQGELV RYLARREEWR RWGGADHLVV PHHPNSMMDA RRRLSAAMFV LSDFGRYPPD 300 VANLRKDVIA PYKHVVPSLG DGDSPGFEQR PVLAYFQGAI HRKNGGRVRQ RLYQLIKDEK 360 DVHFTYGSVR QNGIRRATKG MASSKFCLNI AGDTPSSNRL FDAIVSHCVP VIISDDIELP 420 FEDVLDYSAF CVFVRASDAV KRGFLLHLLR GISQEEWTAM WRRLKEVAHH FEYQYPSQPG 480 DAVQMIWGAV ARKMHLVKLQ LHKRGRYQRT FSES* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-55 | 127 | 452 | 335 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005623 | cell |
| GO:0008150 | biological_process |
| GO:0008152 | metabolic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC83632.1 | 0 | 1 | 514 | 53 | 566 | hypothetical protein OsI_29363 [Oryza sativa Indica Group] |
| RefSeq | NP_001061895.1 | 0 | 1 | 514 | 53 | 566 | Os08g0438600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002284930.1 | 0 | 120 | 510 | 66 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002284932.1 | 0 | 120 | 510 | 27 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002444408.1 | 0 | 4 | 514 | 8 | 539 | hypothetical protein SORBIDRAFT_07g021480 [Sorghum bicolor] |
