| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os09g34920.1 |
| Family | GH29 |
| Protein Properties | Length: 495 Molecular Weight: 53464.3 Isoelectric Point: 7.6603 |
| Chromosome | Chromosome/Scaffold: 9 Start: 20348939 End: 20350901 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH29 | 17 | 343 | 0 |
| IAAVVAATSSSLAEATATPPLPVLPVPTAAQLRWQRREVIMFFHFGMNTFTDSEWGTGREPPAAFRPAALDASQWMDAAAAAGASLVVLVAKHHDGFCLW PSAHTAHSVRASPWRGGRGDVVREFADAARARGLDIGIYLSPWDRHDKRYGREVAYNEYYLAQLHELLTGYGSVSEIWFDGAKGKNATNMTYHFQEWFQT VRQLQSSINIFSDDGPDLRWVGDENGSAGSTCWSTINRSKITIGEAGIEKYLNTGDPRGKDWVPPECDVSIRPGWFWHKNETAKPLPELLEVYYNSVGRN CVLLLNAPPNTTGLVDAADIARLREFR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 495 Download |
| MMGRCASPLC ALAAALIAAV VAATSSSLAE ATATPPLPVL PVPTAAQLRW QRREVIMFFH 60 FGMNTFTDSE WGTGREPPAA FRPAALDASQ WMDAAAAAGA SLVVLVAKHH DGFCLWPSAH 120 TAHSVRASPW RGGRGDVVRE FADAARARGL DIGIYLSPWD RHDKRYGREV AYNEYYLAQL 180 HELLTGYGSV SEIWFDGAKG KNATNMTYHF QEWFQTVRQL QSSINIFSDD GPDLRWVGDE 240 NGSAGSTCWS TINRSKITIG EAGIEKYLNT GDPRGKDWVP PECDVSIRPG WFWHKNETAK 300 PLPELLEVYY NSVGRNCVLL LNAPPNTTGL VDAADIARLR EFRTAVTAIF GTDLAAGSAA 360 RASSERGGRF AAANVLDGRD DTYWAPAAAE AEDGGGYWIE LRRPASAAAR KFNVVRIQEH 420 VAMGQRVERH EVYVDGGGAA VASGTTVGHK RLHRLGAPVA GRTVRVWLAS RRGPPLLSAV 480 GLHLDPFAAG GGTM* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 5.0e-19 | 108 | 342 | 251 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 8.0e-22 | 108 | 353 | 269 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-47 | 47 | 354 | 319 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005515 | protein binding |
| GO:0005773 | vacuole |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABG73453.1 | 0 | 2 | 490 | 1 | 494 | glycosyl hydrolase family 29 [Oryza brachyantha] |
| GenBank | EEC84898.1 | 0 | 1 | 494 | 1 | 494 | hypothetical protein OsI_32076 [Oryza sativa Indica Group] |
| GenBank | EEE70067.1 | 0 | 112 | 494 | 131 | 513 | hypothetical protein OsJ_30048 [Oryza sativa Japonica Group] |
| RefSeq | NP_001063703.1 | 0 | 1 | 494 | 1 | 494 | Os09g0520800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002462685.1 | 0 | 6 | 489 | 2 | 482 | hypothetical protein SORBIDRAFT_02g030220 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 38 | 483 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 38 | 483 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 43 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 43 | 478 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 43 | 478 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
