| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os10g10080.1 |
| Family | GT47 |
| Protein Properties | Length: 418 Molecular Weight: 47299.6 Isoelectric Point: 8.3735 |
| Chromosome | Chromosome/Scaffold: 10 Start: 5487008 End: 5490451 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 50 | 345 | 0 |
| KLKVYVYELPPKYNKNIVAKDSRCLSHMFATEIFMHRFLLSSAIRTSNPDEADWFYTPVYTTCDLTPWGHPLTTKSPRMMRSAIKFISKYWPYWNRTEGA DHFFVVPHDFAACFYFQEAKAIERGILPVLRRATLVQTFGQKNHACLKDGSITVPPYTPAHKIRAHLVPPETPRSIFVYFRGLFYDTSNDPEGGYYARGA RASVWENFKNNPMFDISTDHPQTYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFSDAIPWEEIAVFVAEDDVPQLDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 418 Download |
| MGTRRRSARA RARPPLAMPL AVLLLFACSS GVAAAAAQGI ERIKDDPVGK LKVYVYELPP 60 KYNKNIVAKD SRCLSHMFAT EIFMHRFLLS SAIRTSNPDE ADWFYTPVYT TCDLTPWGHP 120 LTTKSPRMMR SAIKFISKYW PYWNRTEGAD HFFVVPHDFA ACFYFQEAKA IERGILPVLR 180 RATLVQTFGQ KNHACLKDGS ITVPPYTPAH KIRAHLVPPE TPRSIFVYFR GLFYDTSNDP 240 EGGYYARGAR ASVWENFKNN PMFDISTDHP QTYYEDMQRA VFCLCPLGWA PWSPRLVEAV 300 VFGCIPVIIA DDIVLPFSDA IPWEEIAVFV AEDDVPQLDT ILTSIPTEVI LRKQAMLAEP 360 SMKQTMLFPQ PAEPGDGFHQ VMNALARKLP HGRDVFLKPG QKVLNWTEGT REDLKPW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-82 | 50 | 345 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005623 | cell |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAL76189.1 | 0 | 18 | 417 | 1 | 401 | AC092173_1 Unknown protein [Oryza sativa Japonica Group] |
| GenBank | AAM74308.1 | 0 | 18 | 417 | 1 | 401 | AC083944_26 Unknown protein similar to exostosin-2 [Oryza sativa Japonica Group] |
| GenBank | EEC66643.1 | 0 | 18 | 417 | 1 | 400 | hypothetical protein OsI_32904 [Oryza sativa Indica Group] |
| RefSeq | NP_001064248.1 | 0 | 1 | 417 | 1 | 417 | Os10g0180000 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002440185.1 | 0 | 30 | 417 | 21 | 416 | hypothetical protein SORBIDRAFT_09g027450 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
