y
Basic Information | |
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Species | Oryza sativa |
Cazyme ID | LOC_Os10g40559.1 |
Family | GT47 |
Protein Properties | Length: 464 Molecular Weight: 51130.3 Isoelectric Point: 8.9678 |
Chromosome | Chromosome/Scaffold: 10 Start: 21721755 End: 21723342 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 32 | 388 | 0 |
CAGRRIHIRRLPPRFNAHLLRHCDAGFPLADPSTPATSSPPCESLVNHGLGPRTHSSSRSWYRTDTRLLEVFFHRRVAERGCLVADPALADAVYLPYYAG LDSLPYVLDPALLDSSAQHGAELAEFLARDRPQILARRHGHDHFLVLAGSAWDYSQPVRAAAAAAAEARLWGTTSLLRLPALGNLTFLTLESRAWPWQEH AIPHPTSFHPASLPRLRAWLARARRARRPALMLFSGGVSRPSRPNIRGSILAECANRTDACVVVDCSGGRCSHDPIRYMRPMLHSRFCLQPPGDTPTRRS TFDAILAGCVPVFFEDAAARRQYGWHLPPERYDEFSVYIPKESVVFGGVKIAETLAA |
Full Sequence |
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Protein Sequence Length: 464 Download |
MPNPLFFLLL LAAAAAATAG AGEGGATRKD PCAGRRIHIR RLPPRFNAHL LRHCDAGFPL 60 ADPSTPATSS PPCESLVNHG LGPRTHSSSR SWYRTDTRLL EVFFHRRVAE RGCLVADPAL 120 ADAVYLPYYA GLDSLPYVLD PALLDSSAQH GAELAEFLAR DRPQILARRH GHDHFLVLAG 180 SAWDYSQPVR AAAAAAAEAR LWGTTSLLRL PALGNLTFLT LESRAWPWQE HAIPHPTSFH 240 PASLPRLRAW LARARRARRP ALMLFSGGVS RPSRPNIRGS ILAECANRTD ACVVVDCSGG 300 RCSHDPIRYM RPMLHSRFCL QPPGDTPTRR STFDAILAGC VPVFFEDAAA RRQYGWHLPP 360 ERYDEFSVYI PKESVVFGGV KIAETLAAVG EGEVRRMRER ALEMAPRVLY RRHGSTAELS 420 ETAKDAVDLA VDGALRRIRR RVRALDDGEP ERIYSLEDDA VES* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-51 | 31 | 388 | 370 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005623 | cell |
GO:0008152 | metabolic process |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG13471.2 | 0 | 1 | 463 | 1 | 463 | AC026758_8 hypothetical protein [Oryza sativa Japonica Group] |
GenBank | ACF22751.1 | 0 | 30 | 462 | 37 | 460 | exostosin family protein [Brachypodium distachyon] |
GenBank | ACN36955.1 | 0 | 1 | 462 | 1 | 454 | unknown [Zea mays] |
RefSeq | NP_001065337.1 | 0 | 1 | 463 | 140 | 602 | Os10g0553600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002467522.1 | 0 | 1 | 462 | 1 | 449 | hypothetical protein SORBIDRAFT_01g029520 [Sorghum bicolor] |