Basic Information | |
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Species | Oryza sativa |
Cazyme ID | LOC_Os10g40640.1 |
Family | GT8 |
Protein Properties | Length: 493 Molecular Weight: 56029.8 Isoelectric Point: 8.051 |
Chromosome | Chromosome/Scaffold: 10 Start: 21798920 End: 21802986 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 70 | 281 | 5.8e-23 |
YEFYVAVRVMMRSLARIGADADRVLIASADVPADWVRAMREEDGMRVVLVENMKNPYESNLGGINRRFKLTLNKLYAWTLVDYERVVMIDSDNIFLQKTD ELFQCGQFCAVFINPCYFHTGLFVLQPSMDVFKGMLHDLEIGRANSDGADQGFLVGCYPDLLDRPMFHPPENGSKLNGTYRLPLGYQMDASYYYLKLHWH VPCGPNSVITFP |
Full Sequence |
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Protein Sequence Length: 493 Download |
MGWWPPAAWR RWGVVVVVVA ALMAVSATAA VEEELGGRES GVVAAAAQGR WPRHRHAYAA 60 MMYMGTPRDY EFYVAVRVMM RSLARIGADA DRVLIASADV PADWVRAMRE EDGMRVVLVE 120 NMKNPYESNL GGINRRFKLT LNKLYAWTLV DYERVVMIDS DNIFLQKTDE LFQCGQFCAV 180 FINPCYFHTG LFVLQPSMDV FKGMLHDLEI GRANSDGADQ GFLVGCYPDL LDRPMFHPPE 240 NGSKLNGTYR LPLGYQMDAS YYYLKLHWHV PCGPNSVITF PSAPWFKPWY WWSWPILPLG 300 LSWHKQRWDD LGYAAEMPVI LMEILMYAVI ITITRLAKPG MTKLCYNRRP EKQNAMVQGL 360 IKMSAIVAML IAYAIPFFII PRTVHPFMGW SMYLFGALAL GVLVSNAFLL PLLAVLTPWL 420 AIIGMFFVMA FPWYHGGIVR VLAIFGYAFC SAPFLWASLV RVMDSLQTML EREPFFPRLG 480 EPAQETEFSK LF* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
cd00505 | Glyco_transf_8 | 8.0e-5 | 139 | 289 | 180 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. |
COG5597 | COG5597 | 2.0e-5 | 136 | 229 | 103 | + Alpha-N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] |
cd06914 | GT8_GNT1 | 6.0e-7 | 81 | 202 | 131 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. |
pfam01501 | Glyco_transf_8 | 3.0e-8 | 69 | 223 | 190 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. |
cd02537 | GT8_Glycogenin | 8.0e-57 | 56 | 307 | 262 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
Gene Ontology | |
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GO Term | Description |
GO:0005623 | cell |
GO:0005975 | carbohydrate metabolic process |
GO:0009058 | biosynthetic process |
GO:0016740 | transferase activity |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACN33883.1 | 0 | 39 | 492 | 35 | 488 | unknown [Zea mays] |
GenBank | EAY79474.1 | 0 | 1 | 492 | 1 | 492 | hypothetical protein OsI_34602 [Oryza sativa Indica Group] |
RefSeq | NP_001065345.1 | 0 | 1 | 492 | 1 | 492 | Os10g0555100 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001148114.1 | 0 | 39 | 492 | 35 | 488 | transferase, transferring glycosyl groups [Zea mays] |
RefSeq | XP_002467515.1 | 0 | 39 | 492 | 33 | 486 | hypothetical protein SORBIDRAFT_01g029400 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3u2x_B | 0.00000000003 | 78 | 223 | 22 | 168 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
PDB | 3u2x_A | 0.00000000003 | 78 | 223 | 22 | 168 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
PDB | 3u2v_B | 0.00000000003 | 78 | 223 | 22 | 168 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
PDB | 3u2v_A | 0.00000000003 | 78 | 223 | 22 | 168 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
PDB | 3u2u_B | 0.00000000003 | 78 | 223 | 22 | 168 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |