| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os12g12290.1 |
| Family | GT47 |
| Protein Properties | Length: 528 Molecular Weight: 59407.5 Isoelectric Point: 7.0474 |
| Chromosome | Chromosome/Scaffold: 12 Start: 6754961 End: 6756770 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 87 | 455 | 0 |
| SCDGRYVYVLEVPRRFQMLTECVEGPKVFDDPYHVCVVMSNSGLGPVIPPAAAGNATVDGDIIPNTGWYNTDQYALEVIFHNRMRRYECLTSDMAAATAV YVAFYPALELNRHKCGSSATERNEPPREFLRWLTSQPSWAALGGRDHFMVAARTTWMFRRGGAGDSLGCGNGFLSRPESGNMTVLTYESNIWERRDFAVP YPSYFHPSSAREVSAWQATARAARRPWLFAFAGARRANGTLAIRDHIIDECTASPPGRCGMLDCSHGLEGSITCRSPRRLVALFASARFCLQPPGDSFMR RSSIDTVLAGCIPVFFHEASTFKKQYQWHERDADADNDNATVDRRRYSVVIDPDDVVEGRVRIEEVLRR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 528 Download |
| MEANYPKYVL YGLLIVGSWL LSCLLHFQVF HLSLFPYPSY LLSRRVVLPL ALNARFLPPR 60 PDVAGDDDGG IVRRRSSSPA KAAAEASCDG RYVYVLEVPR RFQMLTECVE GPKVFDDPYH 120 VCVVMSNSGL GPVIPPAAAG NATVDGDIIP NTGWYNTDQY ALEVIFHNRM RRYECLTSDM 180 AAATAVYVAF YPALELNRHK CGSSATERNE PPREFLRWLT SQPSWAALGG RDHFMVAART 240 TWMFRRGGAG DSLGCGNGFL SRPESGNMTV LTYESNIWER RDFAVPYPSY FHPSSAREVS 300 AWQATARAAR RPWLFAFAGA RRANGTLAIR DHIIDECTAS PPGRCGMLDC SHGLEGSITC 360 RSPRRLVALF ASARFCLQPP GDSFMRRSSI DTVLAGCIPV FFHEASTFKK QYQWHERDAD 420 ADNDNATVDR RRYSVVIDPD DVVEGRVRIE EVLRRFSDDE VAAMREEVIR MIPRFVYKDP 480 RVRFEGDMRD AFDITFDEIM ARMRRIKNGE ILGWKLDGDD DVVAKDS* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-66 | 88 | 456 | 381 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0008152 | metabolic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA96790.1 | 0 | 1 | 527 | 1 | 527 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| DDBJ | BAH95576.1 | 0 | 155 | 527 | 94 | 466 | Os12g0224400 [Oryza sativa Japonica Group] |
| GenBank | EEC69035.1 | 0 | 104 | 527 | 1 | 391 | hypothetical protein OsI_37846 [Oryza sativa Indica Group] |
| GenBank | EEE52961.1 | 0 | 104 | 527 | 1 | 424 | hypothetical protein OsJ_35605 [Oryza sativa Japonica Group] |
| RefSeq | XP_002443053.1 | 0 | 1 | 521 | 1 | 519 | hypothetical protein SORBIDRAFT_08g007160 [Sorghum bicolor] |
