Basic Information | |
---|---|
Species | Linum usitatissimum |
Cazyme ID | Lus10000608 |
Family | GT47 |
Protein Properties | Length: 634 Molecular Weight: 71758.4 Isoelectric Point: 8.7054 |
Chromosome | Chromosome/Scaffold: 492 Start: 5963 End: 8131 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 306 | 587 | 0 |
NMLKVYVYREGERPVFHQPALRGIYASEGWFMRQMESYKKFVTRDSRKAHLFYLPFGSRNLEEALYVPNSHSHKNLIQYLKDYLDMVSAKHPFWNRTDGA DHFLVACHDWAPAETRQYMSNCIRALCNADVKEGFVFGKDSSLPETNVRNPQKPLRDIGGKSASKRSILAFYAGNMHGYVRPILLQHWQNKDPDIKVYGV MPKSKGNKNYIQHMRSSKYCICPKGYEVNSPRVVEAIFHECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPNLKNILLSI |
Full Sequence |
---|
Protein Sequence Length: 634 Download |
MGKEIGLRCP GESWKLISLI GITFVLAVTF QYIELPYATF WPSTTSSSAS KAIVDPEAKG 60 FNDSFPFVLE NSSNSSNVEA AARDEAADDD DPEDRTENLG KDFVTEGVNK SSGSSDQELL 120 LTNNANSTLV PKNSSADNAS HVSFAPETEG PSVVSPPKES SNNISSTIPK IAEANAPNPA 180 ASVDSMKPAN TNQDINNAKS DKLKTDISNA DDIPSPKKAA DKRRKPTDTT TTPAVLTISE 240 MNRLMLQSWT APNVIKPRWP SAADQQLRHA RSEIEHAPVT ANDPMLYAPI YRNVSMFKRS 300 YELMENMLKV YVYREGERPV FHQPALRGIY ASEGWFMRQM ESYKKFVTRD SRKAHLFYLP 360 FGSRNLEEAL YVPNSHSHKN LIQYLKDYLD MVSAKHPFWN RTDGADHFLV ACHDWAPAET 420 RQYMSNCIRA LCNADVKEGF VFGKDSSLPE TNVRNPQKPL RDIGGKSASK RSILAFYAGN 480 MHGYVRPILL QHWQNKDPDI KVYGVMPKSK GNKNYIQHMR SSKYCICPKG YEVNSPRVVE 540 AIFHECVPVI ISDNFVPPFF EVLNWESFAV FVLEKDIPNL KNILLSISQR RYQQMQMRVK 600 RVQQHFLWHP KPVKYDVFHM ILHSIWYNRV FRT* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-69 | 308 | 587 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 193 | 632 | 153 | 592 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 12 | 632 | 12 | 651 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 632 | 1 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 196 | 632 | 31 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 241 | 633 | 1 | 395 | predicted protein [Populus trichocarpa] |