Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10001917 |
Family | GT47 |
Protein Properties | Length: 517 Molecular Weight: 58671.2 Isoelectric Point: 9.9481 |
Chromosome | Chromosome/Scaffold: 811 Start: 9162 End: 11809 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 181 | 468 | 0 |
EKRFKVYVYKEGEPPIVHDGPCKDIYTVEGRFIHELEHGSSGRKLKTEHPWRAHAYFMPFSVTWMVKYLYTPLSYDLAPLRRFVADYVTVISSKYPFWNR TLGADHFMLACHDWGPHASRGNQLVHDKSIRVLCNANTSEGFNPRKDVSLPEIHLYGGNIPTELLLSPPPNSHRRSYLGFFAGGLHGPIRPILINHWRNR NDPQLKVFEYLPKNQSYYSFMLKSKFCLCPSGHEVASPRIVEAIYAECVPVILSENYVLPFSDVLRWQAFSVTVDVVEIPMLKEILGG |
Full Sequence |
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Protein Sequence Length: 517 Download |
MELKRQKFTS LFSPSLSSST SFLLFISVLI ASAYYFCSYE GRLLRRLATE SHFESSGGGD 60 TTTGSSNVFP AVELHTKIVS SNQIQAVRPS APPSVGNGSF TTNTTSSSSV AQQRKRAAKT 120 ISREEELERG LARARASIRR AAMATDQNSS MMIGRSNGIN FTSGSVYRNP RAFHRSYMEM 180 EKRFKVYVYK EGEPPIVHDG PCKDIYTVEG RFIHELEHGS SGRKLKTEHP WRAHAYFMPF 240 SVTWMVKYLY TPLSYDLAPL RRFVADYVTV ISSKYPFWNR TLGADHFMLA CHDWGPHASR 300 GNQLVHDKSI RVLCNANTSE GFNPRKDVSL PEIHLYGGNI PTELLLSPPP NSHRRSYLGF 360 FAGGLHGPIR PILINHWRNR NDPQLKVFEY LPKNQSYYSF MLKSKFCLCP SGHEVASPRI 420 VEAIYAECVP VILSENYVLP FSDVLRWQAF SVTVDVVEIP MLKEILGGVS EEEYLRLKKG 480 VRAVRKHFVL NQPAKRFDVF HMILHSVWLR RLDIKL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-57 | 180 | 466 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 71 | 516 | 47 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 95 | 516 | 74 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 180 | 516 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 180 | 516 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 72 | 516 | 55 | 480 | catalytic, putative [Ricinus communis] |