Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10002060 |
Family | GT47 |
Protein Properties | Length: 487 Molecular Weight: 54906.7 Isoelectric Point: 9.0585 |
Chromosome | Chromosome/Scaffold: 752 Start: 96789 End: 99199 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 100 | 419 | 0 |
AVLKVYMYDLPPEFHFGLLGWKGTANQRWPDVDDPMHIPSYPGGLTLQHSMEYWLTLDLLASNVPSIVRSCSAVRVDNSSEADVVFVPFFSSLSYNRHSK PLGRQKVGLNKILQDKLVKYLVDQDLWKRYGGKNHLIVAHHPNSMAYSRKKLASAMFVLADFGRYPEKVANIKKDVIAPYKHVVRSVPNAKSARFDQRPT LAYFKGAIYRKDGGATRQELYYLLKDEKDVDFTFGSYGKDGVKKATEGMAGSKFCLHIAGDTPSSNRLFDIIATHCVPVIISDAIELPFEDELDYSEFSV FVHASDAVKPGYLLNLLRGI |
Full Sequence |
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Protein Sequence Length: 487 Download |
MSEKTRTPSR LLFYLITLSL FLLILSSLSL RQFGNVSLLP GSVFGMILVN ETSISSNSDF 60 QTSSNNITPF FSPLASITQS SNEGRACSTS GSLSCDPNNA VLKVYMYDLP PEFHFGLLGW 120 KGTANQRWPD VDDPMHIPSY PGGLTLQHSM EYWLTLDLLA SNVPSIVRSC SAVRVDNSSE 180 ADVVFVPFFS SLSYNRHSKP LGRQKVGLNK ILQDKLVKYL VDQDLWKRYG GKNHLIVAHH 240 PNSMAYSRKK LASAMFVLAD FGRYPEKVAN IKKDVIAPYK HVVRSVPNAK SARFDQRPTL 300 AYFKGAIYRK DGGATRQELY YLLKDEKDVD FTFGSYGKDG VKKATEGMAG SKFCLHIAGD 360 TPSSNRLFDI IATHCVPVII SDAIELPFED ELDYSEFSVF VHASDAVKPG YLLNLLRGIK 420 RDVWTEMWLK LQEISFHFEY RYPSLPGDAV DMIWNAVSRK LDSVRLQVNR KNRYHRAYQN 480 QIEQDN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-55 | 99 | 419 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD55303.1 | 0 | 1 | 477 | 1 | 449 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 477 | 1 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 75 | 477 | 7 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 102 | 476 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 1 | 476 | 1 | 486 | catalytic, putative [Ricinus communis] |