Basic Information | |
---|---|
Species | Linum usitatissimum |
Cazyme ID | Lus10002664 |
Family | GT47 |
Protein Properties | Length: 417 Molecular Weight: 47835.5 Isoelectric Point: 8.1209 |
Chromosome | Chromosome/Scaffold: 1086 Start: 120962 End: 123440 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 92 | 369 | 0 |
EENFKVYIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIRESKFRTEDPDQAHLFFIPISCHKMRGKGTSYENMTIIVQNYVDSLIVKYPYWNRTLGADHF FVTCHDVGVRATEGVPFLVKNAIRAVCSPSYDVGFIPHKDVALPQILQPFALPAGGNDAENRTTLGFWAGHRNSKIRVILARVWENDTELDISNNRISRA TGHLVYQKRFYKTKFCICPGGSQVNSARITDSIHYGCVPVILSNYYDLPFNDIIDWNKFAVVLKEKDVYNLKQILKDI |
Full Sequence |
---|
Protein Sequence Length: 417 Download |
MSSGKFQQQS MLSLKGSLLT LAFITSFYLI YLSLNSLHSS PSPSAPSVIS AAESGKRIVR 60 SETEDTFAND GEEITDLYHF PEIFRLNYAA MEENFKVYIY PDGDPNTFYQ TPRKLTGKYA 120 SEGYFFQNIR ESKFRTEDPD QAHLFFIPIS CHKMRGKGTS YENMTIIVQN YVDSLIVKYP 180 YWNRTLGADH FFVTCHDVGV RATEGVPFLV KNAIRAVCSP SYDVGFIPHK DVALPQILQP 240 FALPAGGNDA ENRTTLGFWA GHRNSKIRVI LARVWENDTE LDISNNRISR ATGHLVYQKR 300 FYKTKFCICP GGSQVNSARI TDSIHYGCVP VILSNYYDLP FNDIIDWNKF AVVLKEKDVY 360 NLKQILKDIP DEQFVELNQN VAKVQKHFQW NSPPIKYDAF HMVMYDLWLR RHVIRY* 420 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-58 | 91 | 369 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 1 | 416 | 1 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 11 | 416 | 19 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 1 | 416 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 11 | 416 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 1 | 416 | 1 | 406 | catalytic, putative [Ricinus communis] |