Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10005567 |
Family | GT47 |
Protein Properties | Length: 343 Molecular Weight: 38675.9 Isoelectric Point: 8.7768 |
Chromosome | Chromosome/Scaffold: 2324 Start: 114871 End: 116539 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 92 | 339 | 7.2e-33 |
SATWFATHQFIGEMTFHARMENHPCRTVNPTVAELFYIPFYGGLHQSSKARENNLTVRDQLAVQLDQHLVWLSKRQGRDHFLVLGRTAWDFMRSDNDGGS DYGANGLLRLMALRNVTVLTVERQPWEGGERQMGIPYPSYFHPFNVDQFMTWQKEVNGLRRPYLWSFIGAPRKGGEIAAVREELRQCYESRKCTLVNCTM SEENGDRFKCHDPKEVVKAPGDSHTRPSTFDAVLTVCIPVFFSRHTAY |
Full Sequence |
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Protein Sequence Length: 343 Download |
MQKFAEIGDS SPNYTSPISS LSSSSPTTSI APPSPTTGRD PPPAAGPPFG VHLPPPLRIQ 60 LRPPPRLRPL ELLHRHVPLR GEPRTVPLLA ESATWFATHQ FIGEMTFHAR MENHPCRTVN 120 PTVAELFYIP FYGGLHQSSK ARENNLTVRD QLAVQLDQHL VWLSKRQGRD HFLVLGRTAW 180 DFMRSDNDGG SDYGANGLLR LMALRNVTVL TVERQPWEGG ERQMGIPYPS YFHPFNVDQF 240 MTWQKEVNGL RRPYLWSFIG APRKGGEIAA VREELRQCYE SRKCTLVNCT MSEENGDRFK 300 CHDPKEVVKA PGDSHTRPST FDAVLTVCIP VFFSRHTAYS QY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-37 | 94 | 334 | 265 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 87 | 342 | 111 | 371 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 87 | 342 | 111 | 371 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 87 | 342 | 163 | 424 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 61 | 342 | 21 | 309 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 76 | 342 | 57 | 330 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FC884199 | 276 | 81 | 342 | 0 |
FC899396 | 276 | 81 | 342 | 0 |
DY298787 | 276 | 81 | 342 | 0 |
DY265125 | 276 | 81 | 342 | 0 |
AM727351 | 257 | 101 | 342 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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