Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10006694 |
Family | GT47 |
Protein Properties | Length: 554 Molecular Weight: 62826.4 Isoelectric Point: 6.106 |
Chromosome | Chromosome/Scaffold: 2932 Start: 175253 End: 177619 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 80 | 425 | 0 |
CLGKYVYIQDLPVRFNQELLDHCESITPGSERNMCPYLLNHGFGQSIQDSSKILSNTSWYLTNQFMLEVIFHSRMKNYKCLTNDSSLASAVYVPFYAGLD ISRYLWGFGASARDRSGFELMKLLSDKPEWRRMYGRDHFMVAGRISWDFRRRTDNDSDWGSKLRFMPESKNMSMLAIESSSWNNDYAIPYPTCFHPSNQK DVSEWQEQLRRKERQYLFSFAGAPRPDLDNSIRGRIMEECQASKNSCKLLECTYAEKGAITCDNPVNVMKVFQDSVFCLQPAGDSYTRRSTFDAILAGCI PVFFHPGTAYAQYKWHLPKDYGRYSVFLPVKDVKDWKAGVNQTLLG |
Full Sequence |
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Protein Sequence Length: 554 Download |
MGKKPSFFPS KFCNFQLWLV CLSSFLLCLL LFCFDYSALL GFGNGGLLDE NSMNPSVAEN 60 LTDSITTLVY LNNHDLTDSC LGKYVYIQDL PVRFNQELLD HCESITPGSE RNMCPYLLNH 120 GFGQSIQDSS KILSNTSWYL TNQFMLEVIF HSRMKNYKCL TNDSSLASAV YVPFYAGLDI 180 SRYLWGFGAS ARDRSGFELM KLLSDKPEWR RMYGRDHFMV AGRISWDFRR RTDNDSDWGS 240 KLRFMPESKN MSMLAIESSS WNNDYAIPYP TCFHPSNQKD VSEWQEQLRR KERQYLFSFA 300 GAPRPDLDNS IRGRIMEECQ ASKNSCKLLE CTYAEKGAIT CDNPVNVMKV FQDSVFCLQP 360 AGDSYTRRST FDAILAGCIP VFFHPGTAYA QYKWHLPKDY GRYSVFLPVK DVKDWKAGVN 420 QTLLGIPEDR VSAMREEVIG LIPGVIYADS GNDFEDAFDL AVKGILERIE RVRKEISEGK 480 DPAIGFAEGD DYKYTFPFNP VSGESTKLLA LISHLPFHLA GEVAWYALVA NRKVIMLHAG 540 TNDSDDHSFA KIG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-67 | 79 | 412 | 349 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB10178.1 | 0 | 17 | 496 | 23 | 472 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | NP_193135.2 | 0 | 17 | 496 | 31 | 511 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 1 | 496 | 6 | 512 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 16 | 488 | 10 | 482 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 13 | 496 | 10 | 521 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |