Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10007426 |
Family | GT47 |
Protein Properties | Length: 508 Molecular Weight: 58523.6 Isoelectric Point: 8.5102 |
Chromosome | Chromosome/Scaffold: 594 Start: 242690 End: 244213 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 77 | 422 | 0 |
CAGRYIYVHDLPDRFNNEIVRNCRYNSLLKWHDMCPSLLNFGLGTQVQDPGKVLMEKSWYVTNQFTLEVIFHHRMKRYDCLTNDSSLASAIFVPYYAGFD VGRHLWGDYNTTVRDALGIELVKWLRNQPEWNKGPKRLFGKDHFFVSGRIAWDLHRSSNDDDTHWGSNLMQLPESKNMTVLSIETTSSSNEFAIPYPTYF HPRGAKQVHQWQKRIRRQKRPYLFSFVGAPRANTADSIRGELMEQCRDSGKRSCKLLNCQCTKCESPVEVMKVLQRSIFCLQPSGDSYTRRSIFDSILAG CIPVFFHPFSAYGQYTWHFPSNYSSYSVYIPEKLVKQGKVSVRKKL |
Full Sequence |
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Protein Sequence Length: 508 Download |
MEQKSSNHTI ACTQLWFAIL IAFSLLLISR RTVDYTSPFI GERREKLAVL FTTLFNSHSD 60 DEPVTTATTT AAANNTCAGR YIYVHDLPDR FNNEIVRNCR YNSLLKWHDM CPSLLNFGLG 120 TQVQDPGKVL MEKSWYVTNQ FTLEVIFHHR MKRYDCLTND SSLASAIFVP YYAGFDVGRH 180 LWGDYNTTVR DALGIELVKW LRNQPEWNKG PKRLFGKDHF FVSGRIAWDL HRSSNDDDTH 240 WGSNLMQLPE SKNMTVLSIE TTSSSNEFAI PYPTYFHPRG AKQVHQWQKR IRRQKRPYLF 300 SFVGAPRANT ADSIRGELME QCRDSGKRSC KLLNCQCTKC ESPVEVMKVL QRSIFCLQPS 360 GDSYTRRSIF DSILAGCIPV FFHPFSAYGQ YTWHFPSNYS SYSVYIPEKL VKQGKVSVRK 420 KLLGISKQEI AAMRQVVVEL IPKVIYRNPE SKPNDFEDAF DIAVNRVLER VAEIRRRDSE 480 EGEEDAAGSW KLKMDGIGKD HEWDEFF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-65 | 77 | 425 | 365 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_180834.1 | 0 | 75 | 484 | 81 | 486 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 74 | 507 | 90 | 521 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002321098.1 | 0 | 58 | 506 | 27 | 477 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518606.1 | 0 | 34 | 507 | 37 | 498 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002518609.1 | 0 | 9 | 507 | 5 | 501 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |