Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10008751 |
Family | GT47 |
Protein Properties | Length: 537 Molecular Weight: 62201.2 Isoelectric Point: 7.6736 |
Chromosome | Chromosome/Scaffold: 13 Start: 202520 End: 204860 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 135 | 420 | 0 |
KLFKIFVYEEGEPPLFHDGPCKNIYSTEGLFLNFIETDHTNFTTPNPEEAHVYFLPFSVVRIVHYLFLPVVRDKAVLERTVLDYVRIISHKYPFWNRSLG ADHFMLSCHDWGPRATWYEKKLYYNSIRVLCNANTSENFNPKKDVSFPEINLPTGEIPSKSNDSPPSESHNRSVLAFFSGRMHGKIRPVLFRYWKGKDDA DVKVYETLPEGVSYQEMMKKSKYCLCPSGHEVASPRIPEAIYADCVPVLISQDYVPPFSDILNWETFSVQVSVEEIYNLKSILMAI |
Full Sequence |
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Protein Sequence Length: 537 Download |
MEEAEDSKQQ QQEARLYYSP TTTPILSAYC YSLLISTLLI ASLLLLPNLH GSSSSSSSWT 60 WWTSTNPHHH ETPPAADPEL EKIEATLAMA RALIKEAASL NCASSAPHHD SDYVPHGIVY 120 RNPCAFHRSY LLMEKLFKIF VYEEGEPPLF HDGPCKNIYS TEGLFLNFIE TDHTNFTTPN 180 PEEAHVYFLP FSVVRIVHYL FLPVVRDKAV LERTVLDYVR IISHKYPFWN RSLGADHFML 240 SCHDWGPRAT WYEKKLYYNS IRVLCNANTS ENFNPKKDVS FPEINLPTGE IPSKSNDSPP 300 SESHNRSVLA FFSGRMHGKI RPVLFRYWKG KDDADVKVYE TLPEGVSYQE MMKKSKYCLC 360 PSGHEVASPR IPEAIYADCV PVLISQDYVP PFSDILNWET FSVQVSVEEI YNLKSILMAI 420 PEKRYLELVT GVRQVRRHFE VNDPPRRFDV FHMIIHSVWL RRLNFRIDSI ASKYTGKIRE 480 NWIPSQLNLL RLIIVSELIR KQLWFIHLDV RRHWCFRWKK VNSGVGRIFT YPDGHI* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-57 | 133 | 420 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28482.1 | 0 | 77 | 467 | 250 | 634 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_187419.1 | 0 | 82 | 467 | 87 | 469 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002320537.1 | 0 | 76 | 466 | 7 | 392 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524591.1 | 0 | 80 | 472 | 121 | 507 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002524592.1 | 0 | 79 | 469 | 3 | 388 | catalytic, putative [Ricinus communis] |