Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10011120 |
Family | GT47 |
Protein Properties | Length: 545 Molecular Weight: 62710.3 Isoelectric Point: 9.9291 |
Chromosome | Chromosome/Scaffold: 1558 Start: 171926 End: 174263 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 197 | 484 | 0 |
RTMKVYIYKEGEKPVFHQSRMRGIYASEGWFMKLIKESKRFVVKDPRRAHLFYIPFSSEMLRKELYGSPKLHTVKDLEQHLQGYVNLVSQKYMFWNRSNG ADHFVVGCHDWAPKLTSSPMRNCIRVLCNANVGKGFRIGKDTTLPVTSIRSQERPTQDIGGKPPYERHILAFFAGGNHGSLRPVLLQHWAADNSRPHHTM KIMGPMPRDVESKRLYREYMKSSKYCICARGHEVHTPRVVEAIYYECVPVIISDNYVPPFFEMLNWEEFAVFVLEKDVPKLKEILSAI |
Full Sequence |
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Protein Sequence Length: 545 Download |
MAFAVWIRRS NIGSIIWRLL VIMGMAVFSL VLMLVQRPSS FFSNGRNGTS WSPLVAHESA 60 SWVIIPASNP IVSDDSNLGE IQYQNDSSSS LSFNIVEDVG DKIESTSKNR KVASVSAAKR 120 VGRKNPTTIS QMNSQMLHSL FSASSMSVQH PSARDRELRS ARMQIENVPI LKRDTGLHAS 180 SFWNVSSFMR SYELMERTMK VYIYKEGEKP VFHQSRMRGI YASEGWFMKL IKESKRFVVK 240 DPRRAHLFYI PFSSEMLRKE LYGSPKLHTV KDLEQHLQGY VNLVSQKYMF WNRSNGADHF 300 VVGCHDWAPK LTSSPMRNCI RVLCNANVGK GFRIGKDTTL PVTSIRSQER PTQDIGGKPP 360 YERHILAFFA GGNHGSLRPV LLQHWAADNS RPHHTMKIMG PMPRDVESKR LYREYMKSSK 420 YCICARGHEV HTPRVVEAIY YECVPVIISD NYVPPFFEML NWEEFAVFVL EKDVPKLKEI 480 LSAIPEEKYV AMQSSVKMVQ QHFLWHRKPL KYDLFHMILH SVWHNRVFEA KVDNFIDDEV 540 ERVP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-63 | 195 | 484 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 72 | 529 | 213 | 709 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 152 | 530 | 1018 | 1391 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 72 | 531 | 213 | 663 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 72 | 531 | 211 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514249.1 | 0 | 195 | 531 | 1 | 332 | catalytic, putative [Ricinus communis] |