y
Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10011121 |
Family | GT47 |
Protein Properties | Length: 442 Molecular Weight: 51483.1 Isoelectric Point: 10.1863 |
Chromosome | Chromosome/Scaffold: 1558 Start: 175886 End: 177776 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 109 | 392 | 0 |
ERTLKVYVYKDGKKPIFHLPILKGLYASEGWFVKLMEGSKQFLVKDPRKAHLFYMPFSSRMLEYTLYVRNSHNRTNLRQYLKEYAGSIAAKYPYWNRTGG ADHFLVACHDWAPYETRHHMEHCPKALCNADVTTGFKIGRDVSLPETYVRAATNPLRDLGGKPPSERHILAFYAGSMHGYLRRILSKHWKDKDPDMKIWG RMPLGVASKMNYISHMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVFDWSAFSIILAEKDIPNLKEILLSV |
Full Sequence |
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Protein Sequence Length: 442 Download |
MKKIKEETSV PILVSGNTSA GVSIPAKKKM RCEMPPKSVT TFDEMNHLLA RHRRSSRAMR 60 PRWSSVRDKE MLAMKSQIEN AAVLVKDPDL YAPLFRNVSQ FKRSYEIMER TLKVYVYKDG 120 KKPIFHLPIL KGLYASEGWF VKLMEGSKQF LVKDPRKAHL FYMPFSSRML EYTLYVRNSH 180 NRTNLRQYLK EYAGSIAAKY PYWNRTGGAD HFLVACHDWA PYETRHHMEH CPKALCNADV 240 TTGFKIGRDV SLPETYVRAA TNPLRDLGGK PPSERHILAF YAGSMHGYLR RILSKHWKDK 300 DPDMKIWGRM PLGVASKMNY ISHMKSSKYC ICPKGYEVNS PRVVESIFYE CVPVIISDNF 360 VPPFFEVFDW SAFSIILAEK DIPNLKEILL SVPEKRYIEL QLGVRKVQRH FLWHAKPVKY 420 DLFLMTLHSI WYNRVYQIKP R* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-65 | 108 | 392 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 6 | 439 | 238 | 711 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 54 | 437 | 1007 | 1390 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 30 | 441 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 34 | 441 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 4 | 441 | 220 | 676 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EG631332 | 278 | 165 | 442 | 0 |
ES808098 | 343 | 77 | 419 | 0 |
JG174792 | 264 | 179 | 442 | 0 |
EV026079 | 246 | 116 | 361 | 0 |
DV712689 | 315 | 18 | 332 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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