Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10012973 |
Family | GT47 |
Protein Properties | Length: 659 Molecular Weight: 74997.9 Isoelectric Point: 9.1455 |
Chromosome | Chromosome/Scaffold: 434 Start: 391679 End: 394635 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 328 | 609 | 0 |
ERTLKVYIYKDGKKPIFHVPILKGLYASEGWFMKLMQGSKQFVVKDPQKAHLFYMPFSSRMLEYSLYVRDSHNRTNLRQHLNEYTEKIAAKYPYWNRTGG ADHFLVACHDWAPYETRQHMDHCIKALCNADVTVGFKLGTDVSLAETFIRAARNPLRGLGGKPPSQRHILAFYAGGMHGYLRPILVKQWKDKDPDMKIFG PMPASSKMNYIQHMKSSKYCICPKGFEVNSPRVVESIFYECVPVIISDNFVPPLFEVFDWKAFSVILPEKDIPNLKQILVSI |
Full Sequence |
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Protein Sequence Length: 659 Download |
MEFHLRLPKF NQIESKKWLI FVVAITIAHL LFQPLLFPYG YNIRSLLPTA NHSMFDQSGM 60 IATAAEQSSV KPGISRNALA VDSSSSTSSL KIDFILRNDN KSDSSGDISH VSEAKGHDQD 120 TDEEEEEDLD DGPAELAVDR DVADDDEVSL KRSSILEFPS EARKALPLYK NATIKSSEEE 180 TNVSRAVPKS PSSVFEAPPV NSQAVPGTTI DAPLEANEKS SVFPAVVKGA SIVSRDKNGR 240 ARSPVKKQTK SEMPPTSITT IDEMNDLLAH HRRSSRAMRP RWSSVRDQEI LAARSEIENA 300 PLLVNDQDLY APLFRNVSQF KRSYELMERT LKVYIYKDGK KPIFHVPILK GLYASEGWFM 360 KLMQGSKQFV VKDPQKAHLF YMPFSSRMLE YSLYVRDSHN RTNLRQHLNE YTEKIAAKYP 420 YWNRTGGADH FLVACHDWAP YETRQHMDHC IKALCNADVT VGFKLGTDVS LAETFIRAAR 480 NPLRGLGGKP PSQRHILAFY AGGMHGYLRP ILVKQWKDKD PDMKIFGPMP ASSKMNYIQH 540 MKSSKYCICP KGFEVNSPRV VESIFYECVP VIISDNFVPP LFEVFDWKAF SVILPEKDIP 600 NLKQILVSIP EKRYIELQVA VRKVQKHFLW HARPVKFDLF HMTLHSIWYN RVYQMKPR* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-63 | 327 | 609 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 654 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 1 | 656 | 1 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 250 | 658 | 200 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 253 | 658 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 1 | 658 | 1 | 676 | catalytic, putative [Ricinus communis] |