Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10013694 |
Family | GT20 |
Protein Properties | Length: 972 Molecular Weight: 109269 Isoelectric Point: 7.4565 |
Chromosome | Chromosome/Scaffold: 1168 Start: 83259 End: 88659 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 93 | 560 | 0 |
RQRLLVVANRLPVSAVRRGEDAWSLEISAGGLVSALLGVKEFEARWIGWAGVNVPDEVGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFHY LGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNKHYEEGDVVWCHDYHLMFLPKCLKDYNRNMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADLVG FHTYDYARHFVSACTRILGLEGTPEGVEDQGKLTRVAAFPIGIDSERFISALNLPQVQEHIKELTERFRGRKVMLGVDRLDMIKGIPQKILAFEKFLEEN PLWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHGLCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKGVLIL SEFAGAAQSLGAGAILVNPWNITEVADSIRQALTMSSEEREKRHHHNFAHVTTHTAQEWAEMFVSELN |
Full Sequence |
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Protein Sequence Length: 972 Download |
MPANQYHGNS TPYPGRVERL LRERELRELR RSNRAEVNGN HNRGESSELE LRFRESDLQK 60 NSYIEQYLEE AAAATRALNK EGGCEGHDGR PLRQRLLVVA NRLPVSAVRR GEDAWSLEIS 120 AGGLVSALLG VKEFEARWIG WAGVNVPDEV GQKALTKALA EKRCIPVFLD EEIVHQYYNG 180 YCNNILWPLF HYLGLPQEDR LATTRSFQSQ FAAYKKANQM FADVVNKHYE EGDVVWCHDY 240 HLMFLPKCLK DYNRNMKVGW FLHTPFPSSE IHRTLPSRSE LLRSVLAADL VGFHTYDYAR 300 HFVSACTRIL GLEGTPEGVE DQGKLTRVAA FPIGIDSERF ISALNLPQVQ EHIKELTERF 360 RGRKVMLGVD RLDMIKGIPQ KILAFEKFLE ENPLWRDKVV LLQIAVPTRT DVPEYQKLTS 420 QVHEIVGRIN GRFGTLTAVP IHHLDRSLDF HGLCALYAVT DVALVTSLRD GMNLVSYEFV 480 ACQASKKGVL ILSEFAGAAQ SLGAGAILVN PWNITEVADS IRQALTMSSE EREKRHHHNF 540 AHVTTHTAQE WAEMFVSELN DTVVEAQLRT RQVPPLLPQE AAINCFLKSH NRLLILGFNA 600 TLTEPVDTPG RRGDQIKEME LKLHPELKES LLKLCRDTKT TIVVLSGSDR GLLDENFGDY 660 DMWLAAEHGM FLRLTKGEWM TTMPEHLNME WVDSVKHVFE YFTERTPRSH FELRETSLVW 720 NYKYAGSCPP PYSYRYFSAN LFVFPSLNGG SNVMVDVEFG RLQARDMLQH LWTGPISNAS 780 VDVVQGSRSV EVRAVGVTKG AAIDRILGEI VHSKQMTTPI DYVLCVGHFL GKDEDVYSFF 840 EPELPSDGLG VMRSKQSESS KPAGERRPSS RKLPGSSSRG GGGAKASSQS KPIQRAVLHP 900 DRLSSTSFSN SNGRRASPEK ISWNVLDLKG DNYFSCAVGR TRTNARYMLG SSDDVVSFLK 960 KLANASSFSL G* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 5.0e-15 | 896 | 967 | 72 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03064 | PLN03064 | 0 | 1 | 967 | 971 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 88 | 849 | 762 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
pfam00982 | Glyco_transf_20 | 0 | 94 | 561 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
TIGR02400 | trehalose_OtsA | 0 | 95 | 561 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAA69879.1 | 0 | 1 | 967 | 1 | 940 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
RefSeq | NP_177979.1 | 0 | 1 | 967 | 1 | 940 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002285632.1 | 0 | 1 | 967 | 1 | 925 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002331300.1 | 0 | 1 | 967 | 1 | 922 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531237.1 | 0 | 1 | 967 | 1 | 924 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 95 | 571 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 95 | 571 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 95 | 571 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 95 | 571 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 95 | 571 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CX546763 | 303 | 83 | 384 | 0 |
CV711307 | 293 | 93 | 385 | 0 |
ES813375 | 391 | 456 | 846 | 0 |
DW069910 | 288 | 181 | 468 | 0 |
CB651133 | 281 | 121 | 401 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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