y
Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10013700 |
Family | GT47 |
Protein Properties | Length: 813 Molecular Weight: 89960.9 Isoelectric Point: 9.2812 |
Chromosome | Chromosome/Scaffold: 1168 Start: 112456 End: 116946 |
Description | Sodium Bile acid symporter family |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 479 | 752 | 0 |
TGEEIFHSRMENHPCRTKDPVRASLFYVPFYGGFHMSSNMHDANHTARDEQAMRLAEHVKLQPWWHRRNGKDHFMVLGRTAWDFMRPDHDHPDHWYDYGP NSMFSHPTVKNMSVFVLERHPWEGHNQHGIPYPSYFHPYTSDQVAHWQRIVRESKRPYLFSFVGAKRKEGESAAIRDELMRQCSDSKQCKLLNCTTDGSK CNDPTRVLRAMKESQFCLQARGDSFTRRSLFDSILAGCIPVVFSQHTAYTQYSMYLPDDTRSYSVFIEEKEVVG |
Full Sequence |
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Protein Sequence Length: 813 Download |
MQSSLASPLS NNNISFNPLL KTTTTSCRHF IHSSSTALPS SLKSDFPSKA LHRPSQLNLQ 60 WSHSPPHSSL PSRSTVARCG ISSNNSSANE VKSIRAWVEA VTEAISTAFP IWVSFGCLLG 120 LLKPASYTWV TPKWTIFGLT LTMLGMGMTL TLDDLSNAFA MPKQLFAGFL LQYSVMPMSA 180 FLVSKMLNLP SHYAAGLILV GCCPGGTASN IVTYIARGNV ALSVLMTAVS TLTAVVMTPF 240 LTAKLAGQYV AVDAAGLLTS TMQVVLLPVL AGAFLNQYFQ SLVKFVSPLM PPIAVGTVAV 300 LCGNAIAQSS SAILMSGKQV VLAACLLHAS GFFFGYVLSR ILGVDTASSR TISIEVGMQN 360 SVLGVVLATQ HFGNPLTAVP CAVSSVCHSI LGSVLAGIWR RSVPPEKQES NVVNLVGLNR 420 MISARLQMGC RFGLDWVYRV FKRGIGKLLT AFFKNLIRLI ATEWFSSRFV SGGRLFQFTG 480 EEIFHSRMEN HPCRTKDPVR ASLFYVPFYG GFHMSSNMHD ANHTARDEQA MRLAEHVKLQ 540 PWWHRRNGKD HFMVLGRTAW DFMRPDHDHP DHWYDYGPNS MFSHPTVKNM SVFVLERHPW 600 EGHNQHGIPY PSYFHPYTSD QVAHWQRIVR ESKRPYLFSF VGAKRKEGES AAIRDELMRQ 660 CSDSKQCKLL NCTTDGSKCN DPTRVLRAMK ESQFCLQARG DSFTRRSLFD SILAGCIPVV 720 FSQHTAYTQY SMYLPDDTRS YSVFIEEKEV VGRKMNVEKE LEKIGSWEVG EMRKVVVDLI 780 PRLTFAHPDA GGDKGFEDAV DIAISSLLRE VK* 840 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam13593 | DUF4137 | 3.0e-16 | 169 | 401 | 251 | + SBF-like CPA transporter family (DUF4137). These family members are membrane transporter proteins of the CPA and AT superfamily. | ||
pfam01758 | SBF | 7.0e-35 | 157 | 301 | 156 | + Sodium Bile acid symporter family. This family consists of Na+/bile acid co-transporters. These transmembrane proteins function in the liver in the uptake of bile acids from portal blood plasma a process mediated by the co-transport of Na+. Also in the family is ARC3 from S. cerevisiae, this is a putative transmembrane protein involved in resistance to arsenic compounds. | ||
pfam03016 | Exostosin | 7.0e-55 | 477 | 764 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
TIGR00841 | bass | 1.0e-66 | 162 | 401 | 244 | + bile acid transporter. The Bile Acid:Na+ Symporter (BASS) Family (TC 2.A.28) Functionally characterized members of the BASS family catalyze Na+:bile acid symport. These systems have been identified in intestinal, liver and kidney tissues of animals. These symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts. Functionally uncharacterised homologues are found in plants, yeast, archaea and bacteria [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]. | ||
COG0385 | COG0385 | 8.0e-72 | 105 | 410 | 310 | + Predicted Na+-dependent transporter [General function prediction only] |
Gene Ontology | |
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GO Term | Description |
GO:0006814 | sodium ion transport |
GO:0008508 | bile acid:sodium symporter activity |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20101.1 | 0 | 1 | 409 | 1 | 419 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_565182.1 | 0 | 39 | 409 | 28 | 401 | bile acid:sodium symporter family protein [Arabidopsis thaliana] |
RefSeq | XP_002283695.1 | 0 | 1 | 409 | 1 | 420 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002331304.1 | 0 | 143 | 409 | 1 | 267 | bile acid:Na+ symporter family protein [Populus trichocarpa] |
RefSeq | XP_002531245.1 | 0 | 1 | 409 | 1 | 404 | sodium-bile acid cotransporter, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3zuy_A | 0 | 101 | 408 | 7 | 314 | A Chain A, Crystal Structure Of A Bacterial Homologue Of The Bile Acid Sodium Symporter Asbt |
PDB | 3zux_A | 0 | 101 | 408 | 12 | 319 | A Chain A, Crystal Structure Of A Bacterial Homologue Of The Bile Acid Sodium Symporter Asbt |