Basic Information | |
---|---|
Species | Linum usitatissimum |
Cazyme ID | Lus10015243 |
Family | GT20 |
Protein Properties | Length: 947 Molecular Weight: 106377 Isoelectric Point: 6.9782 |
Chromosome | Chromosome/Scaffold: 924 Start: 126568 End: 131676 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT20 | 76 | 544 | 0 |
RKQRLLVVANRLPVSATRKDEDSWHLEISVGGLVSALLGVKEFDARWIGWAGVHVPDETGQKALTEALAKKRCIPVFLDEDTVHQYYNGYCNNVLWPLFH YLGLPQEDRLSTTRSFQSQFDAYKRANRMFADVVNEHYEEGDVVWCHDYHLMFLPKCLKEHNSKMKVGWFLHTPFPSSEIHRMLPSRSELLRSVLAADLV GFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSDRFIRALDLPKVKESMRDLKQRFAGRKLMLGVDRLDMIKGIPQKILAFEAFLEE NPQWREKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGKFGTLTSVPIHHLDRSLDFTALVALYAVTDVALVTSLRDGMNLVSYEFVACQAAKKGVLI LSEFAGAAQSLGAGALLVNPWNISDVANSIRYALNMSEDEREKRFHHNFMHVTTHTSQEWAATFVSELN |
Full Sequence |
---|
Protein Sequence Length: 947 Download |
MPGNNFSHSP TTPRTRLERL LRERELRKSS RVPFPTDQEN GDGFSEAEFF AQDSILSNDE 60 SPEGSDGGSG KEVRPRKQRL LVVANRLPVS ATRKDEDSWH LEISVGGLVS ALLGVKEFDA 120 RWIGWAGVHV PDETGQKALT EALAKKRCIP VFLDEDTVHQ YYNGYCNNVL WPLFHYLGLP 180 QEDRLSTTRS FQSQFDAYKR ANRMFADVVN EHYEEGDVVW CHDYHLMFLP KCLKEHNSKM 240 KVGWFLHTPF PSSEIHRMLP SRSELLRSVL AADLVGFHTY DYARHFVSAC TRILGLEGTP 300 EGVEDQGRLT RVAAFPIGID SDRFIRALDL PKVKESMRDL KQRFAGRKLM LGVDRLDMIK 360 GIPQKILAFE AFLEENPQWR EKVVLLQIAV PTRTDVPEYQ KLTSQVHEIV GRINGKFGTL 420 TSVPIHHLDR SLDFTALVAL YAVTDVALVT SLRDGMNLVS YEFVACQAAK KGVLILSEFA 480 GAAQSLGAGA LLVNPWNISD VANSIRYALN MSEDEREKRF HHNFMHVTTH TSQEWAATFV 540 SELNDTVVEA QLRTRQVLPV LPVEDAIARY SCSNNRLLIL GFNGSLTEPV DSSGRRGGQI 600 RELEPRLHPE LKEILKKLCE HPELKEILKK LCDEAKTTVI VLSGSDRSVL DDNFDEYKMW 660 LAAENGMFLR LAMGGEWMTT MPETLNMDWV DSVKHVFEYF TERTPRSHFE LRETSLVWNY 720 KYADVAFGRL QARDMLQHLW TGPISNASLD VVHGGRSVEV RAVGVTKGAA IDRILGEIVH 780 NKDMKAPIDY VLCIGHFLAK DEDIYTFFEP VLPMPPQITS RATSPDPYGT SRASKPKLPG 840 GSRAPKSQVH LMKQRSLSTL ERSSFGISSW RRDDNRGGPS PSSSATAATS SSSSSRYEGS 900 SVLDLKGDNY FSCAVSKKRS NARYLLRSSN DVVVLLKELS DTVPDG* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 9.0e-9 | 900 | 940 | 41 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03064 | PLN03064 | 0 | 73 | 946 | 875 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 72 | 827 | 756 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PRK14501 | PRK14501 | 0 | 79 | 795 | 722 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 79 | 545 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_177979.1 | 0 | 1 | 943 | 1 | 939 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002305707.1 | 0 | 21 | 942 | 1 | 895 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331300.1 | 0 | 1 | 941 | 1 | 919 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522296.1 | 0 | 1 | 942 | 1 | 911 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
RefSeq | XP_002531237.1 | 0 | 1 | 940 | 1 | 920 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 79 | 555 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 79 | 555 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 79 | 555 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 79 | 555 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 79 | 564 | 3 | 476 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
DW069910 | 288 | 165 | 452 | 0 |
CV711307 | 293 | 77 | 369 | 0 |
CX546763 | 292 | 77 | 368 | 0 |
CB651133 | 280 | 106 | 385 | 0 |
ES813375 | 407 | 440 | 841 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|