| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10016058 |
| Family | GT47 |
| Protein Properties | Length: 341 Molecular Weight: 39087.6 Isoelectric Point: 6.7362 |
| Chromosome | Chromosome/Scaffold: 172 Start: 474815 End: 476180 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 2 | 288 | 0 |
| ERVFKMYVYKEGEPPIFHDGPCKSIYSSEGRFIHEMEKGPDRNLYVTEDPDEALMYFLPFSVVRMVQYLYGEDGSRDTEGIGRVVVDYIDVVSAKYPFWN RSLGADHFMLSCHDWGPRATRYNKELYSNSIRVLCNANTSEGFNPSKDASFPEIHLRTGEITGLIGGPSPSQRSILAFFAGRLHGHIRKLLLDEWKDKLD QDVQVFDSLPPGVSYESKLRNSKFCLCPSGYEVASPRVVEAIYAECVPVLISDAYVPPFSDVLNWKAFSVEIEVKNIHRIKEILMGI | |||
| Full Sequence |
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| Protein Sequence Length: 341 Download |
| MERVFKMYVY KEGEPPIFHD GPCKSIYSSE GRFIHEMEKG PDRNLYVTED PDEALMYFLP 60 FSVVRMVQYL YGEDGSRDTE GIGRVVVDYI DVVSAKYPFW NRSLGADHFM LSCHDWGPRA 120 TRYNKELYSN SIRVLCNANT SEGFNPSKDA SFPEIHLRTG EITGLIGGPS PSQRSILAFF 180 AGRLHGHIRK LLLDEWKDKL DQDVQVFDSL PPGVSYESKL RNSKFCLCPS GYEVASPRVV 240 EAIYAECVPV LISDAYVPPF SDVLNWKAFS VEIEVKNIHR IKEILMGISQ EQYLTMQRSV 300 KQVQRHFVAN GPPKRYDVFH MTVHSIWLRR LNIRVQDSDL * |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 3.0e-57 | 1 | 288 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAU04753.1 | 0 | 1 | 337 | 12 | 343 | EXO [Cucumis melo] |
| EMBL | CBI28483.1 | 0 | 1 | 337 | 85 | 416 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002264076.1 | 0 | 1 | 337 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320538.1 | 0 | 1 | 337 | 1 | 332 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524591.1 | 0 | 1 | 337 | 173 | 504 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG631371 | 250 | 88 | 337 | 0 |
| DT001362 | 239 | 17 | 255 | 0 |
| GW864815 | 309 | 17 | 325 | 0 |
| GO373511 | 253 | 84 | 336 | 0 |
| CX643922 | 247 | 91 | 337 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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