| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10017827 |
| Family | AA3 |
| Protein Properties | Length: 567 Molecular Weight: 61278.5 Isoelectric Point: 8.3294 |
| Chromosome | Chromosome/Scaffold: 35 Start: 25197 End: 28772 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 44 | 557 | 0 |
| APEVSYYDYIIVGGGTAGCPLAATLSQNASVLVLERGGSPYGNPNITNLANFGAPLSDNSPYSPAQRFISEDGVINSRARVLGGGTCLNAGFYSRASADY IREVGWNVKLAEESYQWVEKKVAFRPPMGPWQSAIRDALVHSGVAPNNGFTYDHIYGTKFGGSIFDTSGHRHTSADLLDYANPDRLTVLLKATTRKILFR TKGRARPTAQGVSFRDAAGVKHRAYLRKGAHNEIIIAAGALGSPQLLMLSGVGPAHQLSYHNITVILDQPMVGQLMSDNPMNAVFVPSPVPVEVSLIEVV GITHFGGYIEAASGVNFGGYSNNDHGLFSPKIGQSSDATYNTSKVDMSAFQGGFILQKIMGPLSTGHLKLISRNPNKNPSVTFNYFKHPQDLDRCVQGMS MIEKVIDSKFFSKFKYDFMSVPDLLNLTASAVMNLLPKHDNSATSLEQFCKDTVVTIWHYHGGCQVGAVVGSDYKVLGVDALRVIDGSTFNASPGTNPQA TVMMLGRYMGVKML | |||
| Full Sequence |
|---|
| Protein Sequence Length: 567 Download |
| MGSFYGLVGV HFFFFFYVFQ GCSPSAANQA DDRNYKFVHD ATTAPEVSYY DYIIVGGGTA 60 GCPLAATLSQ NASVLVLERG GSPYGNPNIT NLANFGAPLS DNSPYSPAQR FISEDGVINS 120 RARVLGGGTC LNAGFYSRAS ADYIREVGWN VKLAEESYQW VEKKVAFRPP MGPWQSAIRD 180 ALVHSGVAPN NGFTYDHIYG TKFGGSIFDT SGHRHTSADL LDYANPDRLT VLLKATTRKI 240 LFRTKGRARP TAQGVSFRDA AGVKHRAYLR KGAHNEIIIA AGALGSPQLL MLSGVGPAHQ 300 LSYHNITVIL DQPMVGQLMS DNPMNAVFVP SPVPVEVSLI EVVGITHFGG YIEAASGVNF 360 GGYSNNDHGL FSPKIGQSSD ATYNTSKVDM SAFQGGFILQ KIMGPLSTGH LKLISRNPNK 420 NPSVTFNYFK HPQDLDRCVQ GMSMIEKVID SKFFSKFKYD FMSVPDLLNL TASAVMNLLP 480 KHDNSATSLE QFCKDTVVTI WHYHGGCQVG AVVGSDYKVL GVDALRVIDG STFNASPGTN 540 PQATVMMLGR YMGVKMLSER LASTEG* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05199 | GMC_oxred_C | 6.0e-24 | 405 | 549 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 2.0e-26 | 51 | 549 | 554 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 1.0e-30 | 51 | 549 | 569 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 1.0e-40 | 50 | 564 | 564 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 23 | 566 | 571 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 34 | 563 | 31 | 574 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001053612.1 | 0 | 30 | 563 | 29 | 583 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282510.1 | 0 | 38 | 563 | 1 | 540 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 13 | 565 | 16 | 574 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 4 | 565 | 8 | 546 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 37 | 563 | 14 | 520 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3gdp_A | 0 | 37 | 563 | 14 | 520 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
| PDB | 3gdn_B | 0 | 37 | 563 | 14 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 37 | 563 | 14 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 37 | 563 | 14 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
