| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10018930 |
| Family | GT47 |
| Protein Properties | Length: 358 Molecular Weight: 41495.1 Isoelectric Point: 9.9718 |
| Chromosome | Chromosome/Scaffold: 103 Start: 582405 End: 584123 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 14 | 280 | 0 |
| VKGQWGTQVKIHKLLLKSRFRTKKKEDADLFFVPTYVKCVRMMGGLTDKEINQTFVRVLSQMPYFRRSGGRDHIFVFPSGAGAHLFRSWATFINRSIILT PEGDRTDKKDTTAFNTWKDIIIPGNVEDGMTIRKPATVDPLPLSKRKYLANYLGRAQGKAGRLKLIELSKQYPDKLECPDLKFSGSDKFGRAEYFEHLRN AKFCLAPRGESSWTLRFYESFFVECVPVILSDQAEFPFQNVIDYTQISIKWPSTRIGLELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 358 Download |
| MRGRDGKIAA EACVKGQWGT QVKIHKLLLK SRFRTKKKED ADLFFVPTYV KCVRMMGGLT 60 DKEINQTFVR VLSQMPYFRR SGGRDHIFVF PSGAGAHLFR SWATFINRSI ILTPEGDRTD 120 KKDTTAFNTW KDIIIPGNVE DGMTIRKPAT VDPLPLSKRK YLANYLGRAQ GKAGRLKLIE 180 LSKQYPDKLE CPDLKFSGSD KFGRAEYFEH LRNAKFCLAP RGESSWTLRF YESFFVECVP 240 VILSDQAEFP FQNVIDYTQI SIKWPSTRIG LELLEYLESI PEEEIERMIA NGRRIRCLWV 300 YGSVSEPCST MLGIMWELQR KVRQFHQSHE TFWLHNRTVV NRNLVEFSKW KPPMYLP* 360 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-42 | 13 | 270 | 270 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM61682.1 | 0 | 1 | 357 | 106 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 357 | 106 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002300942.1 | 0 | 1 | 357 | 104 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 357 | 104 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 357 | 97 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 44 | 334 | 0 |
| FE707914 | 279 | 24 | 302 | 0 |
| FE707913 | 274 | 85 | 358 | 0 |
| EH692645 | 270 | 61 | 330 | 0 |
| AJ793618 | 232 | 19 | 250 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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