| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10025178 |
| Family | GT47 |
| Protein Properties | Length: 487 Molecular Weight: 54846.8 Isoelectric Point: 7.9363 |
| Chromosome | Chromosome/Scaffold: 305 Start: 705628 End: 707431 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 148 | 434 | 0 |
| ERVFKMYVYKEGEPPIFHDGPCRSIYSSEGRFIHEMEKGAVSNLYVTEDPEEALVYFLPFSVVRMVQYLYEDDGSRDTEGIGRAVVDYIDVISAKYLFWN RSLGADHFMLSCHDWGPRATSYNKELYNNSIRVLCNANTSEGFNPSKDASFPEIHLRTGEITGLIGGPSPSQRSILAFFAGRLHGHIRKLLLDQWKDKLD QDVQVFDSLPPGVSYESKLRNSKFCLCPSGYEVASPRVVEAIYAECVPVLISDGYVPPFSDVLNWKAFSVEIEVKNIHRIKEILMGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 487 Download |
| MRLPDHHPTS PPPPPSSSFP ISFILITIPL LLISAFAFFA LSNPPAVLIS FPHPAPATHH 60 SHPDDLSTIK PSSSNSTPKP TPPSPSVVLV KRYSKLEKAE ANLAKVRSLI RAAAARIGNL 120 TLEDPDYVPK GAIYRNANAF HKSYLEMERV FKMYVYKEGE PPIFHDGPCR SIYSSEGRFI 180 HEMEKGAVSN LYVTEDPEEA LVYFLPFSVV RMVQYLYEDD GSRDTEGIGR AVVDYIDVIS 240 AKYLFWNRSL GADHFMLSCH DWGPRATSYN KELYNNSIRV LCNANTSEGF NPSKDASFPE 300 IHLRTGEITG LIGGPSPSQR SILAFFAGRL HGHIRKLLLD QWKDKLDQDV QVFDSLPPGV 360 SYESKLRNSK FCLCPSGYEV ASPRVVEAIY AECVPVLISD GYVPPFSDVL NWKAFSVEIE 420 VKNIHRIKEI LMGISQEQYL TMQRRVKQVQ RHFVANGPTK RYDVFHMTVH SIWLRRLNIR 480 VQDSDL* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 2.0e-55 | 147 | 434 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAU04753.1 | 0 | 142 | 483 | 7 | 343 | EXO [Cucumis melo] |
| EMBL | CBI28483.1 | 0 | 121 | 483 | 59 | 416 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002264076.1 | 0 | 147 | 483 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320538.1 | 0 | 147 | 483 | 1 | 332 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524591.1 | 0 | 86 | 483 | 111 | 504 | catalytic, putative [Ricinus communis] |
