| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10027406 |
| Family | AA3 |
| Protein Properties | Length: 598 Molecular Weight: 65805.1 Isoelectric Point: 8.2273 |
| Chromosome | Chromosome/Scaffold: 96 Start: 143749 End: 145943 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 56 | 580 | 0 |
| YFDYIIIGGGTAGCPLAATLSQNATVLVLERGGTPYRDMNITDVANFVSTISDTSPDSPSQIFVSEDGVYNTRARVLGGGSAINAGFYSHSEPEFVSDAG WDEDLVRRSYDWVEAKLAFEPQVLRWQSAVRDALVEIGVLPYNGFTYNHVDGTKIGGTIFDRQGHRHTAADLLEYAEPGNLRVYLHATVSRILFTERARQ WPKPRAYGVMFEDALGVRKRAFLRPHPRNEVILTAGAIGSPQVMMLSGIGPATHLRSHGIPVVLDQPNVGQGMADNPMNLLYVPSPFPVEISLIQVVGTP ANQNNFIETASGLSFAYSWAQGFARDYVSFFNQTGKPSSLTAETMARAIETVHAYANTSLKGGVILEKVKGPLSSGDLKLRSRRPWENPAVTFNYFKHPQ DLSSCVEGIHNIISLINAPSFARLRYPHLPIQALVDLMLNLPVNLRPRHVSSSMSLEQFCIDTVMTIWHYHGGCQVGKVVDQDYRVNGVDALRIIDGSTF LKSPGTNPQATVMMLGRYMGSRILD | |||
| Full Sequence |
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| Protein Sequence Length: 598 Download |
| MIITAPASPS HLTMRFIAPL LAIIFLLNAV CHSQKDATAQ HYTFVHDATR APPVMYFDYI 60 IIGGGTAGCP LAATLSQNAT VLVLERGGTP YRDMNITDVA NFVSTISDTS PDSPSQIFVS 120 EDGVYNTRAR VLGGGSAINA GFYSHSEPEF VSDAGWDEDL VRRSYDWVEA KLAFEPQVLR 180 WQSAVRDALV EIGVLPYNGF TYNHVDGTKI GGTIFDRQGH RHTAADLLEY AEPGNLRVYL 240 HATVSRILFT ERARQWPKPR AYGVMFEDAL GVRKRAFLRP HPRNEVILTA GAIGSPQVMM 300 LSGIGPATHL RSHGIPVVLD QPNVGQGMAD NPMNLLYVPS PFPVEISLIQ VVGTPANQNN 360 FIETASGLSF AYSWAQGFAR DYVSFFNQTG KPSSLTAETM ARAIETVHAY ANTSLKGGVI 420 LEKVKGPLSS GDLKLRSRRP WENPAVTFNY FKHPQDLSSC VEGIHNIISL INAPSFARLR 480 YPHLPIQALV DLMLNLPVNL RPRHVSSSMS LEQFCIDTVM TIWHYHGGCQ VGKVVDQDYR 540 VNGVDALRII DGSTFLKSPG TNPQATVMML GRYMGSRILD GRVATSTWRR PPWRQIP* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 5.0e-23 | 215 | 330 | 123 | + choline dehydrogenase; Validated | ||
| TIGR03970 | Rv0697 | 3.0e-30 | 58 | 571 | 554 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 6.0e-34 | 58 | 579 | 572 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 4.0e-42 | 57 | 579 | 575 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 57 | 583 | 535 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB11043.1 | 0 | 20 | 572 | 12 | 563 | mandelonitrile lyase-like protein [Arabidopsis thaliana] |
| RefSeq | NP_001119417.1 | 0 | 45 | 582 | 1 | 543 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | NP_200008.1 | 0 | 20 | 582 | 12 | 576 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002267848.1 | 0 | 16 | 582 | 9 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002510860.1 | 0 | 15 | 584 | 7 | 572 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 33 | 585 | 3 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 33 | 585 | 3 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 33 | 585 | 3 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 33 | 585 | 3 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 33 | 585 | 3 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
