| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10028632 |
| Family | GT47 |
| Protein Properties | Length: 465 Molecular Weight: 53083.1 Isoelectric Point: 9.2552 |
| Chromosome | Chromosome/Scaffold: 346 Start: 495313 End: 497372 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 91 | 387 | 0 |
| VKIYVYEESEIDGLKELMRGREGKITAEACVKGQWGTQVKIHKLLLKSRFRTKKKEDADLFFVPTYVKCVRMMGGLTDKEINQTFVRVLSQMPYFRRSGG RDHIFVFPSGAGAHLFRSWATFINRSIILTPEGDRTDKKDTTAFNTWKDIIIPGNVEDGMTIRKPTTVEPLPLSKRKYLANYLGRAQGKAGRLKLIELSN QYPDKLECPDLKFSGSDKFGRAEYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVILSDQAEFPFQNVIDYTQISIKWPSTRIGLELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 465 Download |
| MAGSLTNKPP PTRVFSAHHG NTTPCTRVHQ IGALLLVAAT YFLTRLFHDS LSPCVSSIGG 60 GGDLISRSLV HVSDSGQLFW PDRGYGTVLS VKIYVYEESE IDGLKELMRG REGKITAEAC 120 VKGQWGTQVK IHKLLLKSRF RTKKKEDADL FFVPTYVKCV RMMGGLTDKE INQTFVRVLS 180 QMPYFRRSGG RDHIFVFPSG AGAHLFRSWA TFINRSIILT PEGDRTDKKD TTAFNTWKDI 240 IIPGNVEDGM TIRKPTTVEP LPLSKRKYLA NYLGRAQGKA GRLKLIELSN QYPDKLECPD 300 LKFSGSDKFG RAEYFEHLRN AKFCLAPRGE SSWTLRFYES FFVECVPVIL SDQAEFPFQN 360 VIDYTQISIK WPSTRIGLEL LEYLESIPEE EIERMIANGR RIRCLWMYGS ESEPCSTMLG 420 VMWELQRKVR QFHQSHETFW LHNRTVVNRN LVEFSKWEPP MSLP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-42 | 91 | 377 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM61682.1 | 0 | 1 | 464 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 464 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002300942.1 | 0 | 3 | 464 | 2 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 3 | 464 | 2 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 464 | 1 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 151 | 441 | 0 |
| HO781282 | 324 | 25 | 348 | 0 |
| BX841155 | 339 | 1 | 337 | 0 |
| DY295548 | 352 | 1 | 350 | 0 |
| HO781282 | 37 | 341 | 377 | 0.00000000004 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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