| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10031663 |
| Family | AA3 |
| Protein Properties | Length: 594 Molecular Weight: 65614 Isoelectric Point: 8.2279 |
| Chromosome | Chromosome/Scaffold: 783 Start: 62409 End: 64798 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 51 | 578 | 0 |
| MYFDYIIIGGGTAGCPLAATLSQNATVLVLERGGTPYRDMNITDVANFVSTISDTSPESPSQIFVSEDGVYNTRARVLGGGSAINAGFYSHAEPEFVSDA GWDEDLVRRSYDWVEAKLVFEPQVLRWQSAVRDALVEIGVLPYNEFTYNHVDGTKIGGTIFDRQGHRHTAADLLEYAEPGNLKVYLHATVSRILFTERVR QWPKPRAYGVIFEDALGVRKRAFLRPHSRNEVILTAGAIGSPQVMMLSGIGPAMHLRSHGIPVVLDQPNVGQGMADNPMNLLYVPSPYPVEISLIQVVGT PANQNNFIETASGLSFAYSWAQGFARDYVSFFNQTGKPSSLTAETMARAIETVHAYANTSLKGGVILEKVKGPLSSGDLKLRSRRPWENPAVTFNYFKHP QDLSSCVEGIHNIISLINAPSFARLRYPHLPVQALVDLMLNLPVNLRPRHVSSSMSLEQFCIDTVMTIWHYHGGCQVGKVVDQDYRVNGVDALRIIDGST FLKSPGTNPQATVMMLGRYMGSRILEGR | |||
| Full Sequence |
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| Protein Sequence Length: 594 Download |
| MITWPANPSH LTMRFIAPLL GIVFLLNGVC HSQKAQHYAF VHEATRAPPV MYFDYIIIGG 60 GTAGCPLAAT LSQNATVLVL ERGGTPYRDM NITDVANFVS TISDTSPESP SQIFVSEDGV 120 YNTRARVLGG GSAINAGFYS HAEPEFVSDA GWDEDLVRRS YDWVEAKLVF EPQVLRWQSA 180 VRDALVEIGV LPYNEFTYNH VDGTKIGGTI FDRQGHRHTA ADLLEYAEPG NLKVYLHATV 240 SRILFTERVR QWPKPRAYGV IFEDALGVRK RAFLRPHSRN EVILTAGAIG SPQVMMLSGI 300 GPAMHLRSHG IPVVLDQPNV GQGMADNPMN LLYVPSPYPV EISLIQVVGT PANQNNFIET 360 ASGLSFAYSW AQGFARDYVS FFNQTGKPSS LTAETMARAI ETVHAYANTS LKGGVILEKV 420 KGPLSSGDLK LRSRRPWENP AVTFNYFKHP QDLSSCVEGI HNIISLINAP SFARLRYPHL 480 PVQALVDLML NLPVNLRPRH VSSSMSLEQF CIDTVMTIWH YHGGCQVGKV VDQDYRVNGV 540 DALRIIDGST FLKSPGTNPQ ATVMMLGRYM GSRILEGRVA TSTWRRPPWR HIP* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 4.0e-23 | 211 | 326 | 123 | + choline dehydrogenase; Validated | ||
| TIGR03970 | Rv0697 | 2.0e-32 | 54 | 567 | 562 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 3.0e-36 | 54 | 575 | 570 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 3.0e-44 | 53 | 576 | 576 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 53 | 579 | 535 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI31862.1 | 0 | 15 | 578 | 9 | 537 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_200008.1 | 0 | 22 | 578 | 15 | 576 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002267807.1 | 0 | 15 | 578 | 9 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002267848.1 | 0 | 15 | 578 | 9 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002510860.1 | 0 | 14 | 580 | 7 | 572 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 36 | 581 | 10 | 520 | A Chain A, The Crystal Structure Of A Cyanogenic Beta-Glucosidase From White Clover (Trifolium Repens L.), A Family 1 Glycosyl-Hydrolase |
| PDB | 3gdp_A | 0 | 36 | 581 | 10 | 520 | A Chain A, The Crystal Structure Of A Cyanogenic Beta-Glucosidase From White Clover (Trifolium Repens L.), A Family 1 Glycosyl-Hydrolase |
| PDB | 3gdn_B | 0 | 36 | 581 | 10 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 36 | 581 | 10 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 36 | 581 | 10 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
