| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10031681 |
| Family | GH29 |
| Protein Properties | Length: 499 Molecular Weight: 55364.6 Isoelectric Point: 7.6824 |
| Chromosome | Chromosome/Scaffold: 783 Start: 189154 End: 193182 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH29 | 36 | 349 | 0 |
| ATPPLPVLPLPSFSQLKWQQREIIMFFHFGVNTFTDSEWGTGHESPSLFNPTGLNAGQWIDAASVAGVSLVILTAKHHDGFCLWPSKYADHSVAASPWKG GRGDVVGELVGAAEKHGGDVDVGIYLSPWDRHDRRYGKEVEYNEYYLAQLQELLTKYGNVKEIWFDGAKGSNAPNMSYYFSDWFATVKELQSTINIFSDA GPDVRWVGNEKGFAGKTCWSTINRTALSIGNESIVDYLNKGDPKGTDWLPAECDVSIRPGWFWHKSESPKKLSQLLEIYYNSVGRNCLLLLNVPPNTTGL ISETDVNRLREFRA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 499 Download |
| MALINNPHFS LLLSLSSLYL LQNLIAAAAA SKYNVATPPL PVLPLPSFSQ LKWQQREIIM 60 FFHFGVNTFT DSEWGTGHES PSLFNPTGLN AGQWIDAASV AGVSLVILTA KHHDGFCLWP 120 SKYADHSVAA SPWKGGRGDV VGELVGAAEK HGGDVDVGIY LSPWDRHDRR YGKEVEYNEY 180 YLAQLQELLT KYGNVKEIWF DGAKGSNAPN MSYYFSDWFA TVKELQSTIN IFSDAGPDVR 240 WVGNEKGFAG KTCWSTINRT ALSIGNESIV DYLNKGDPKG TDWLPAECDV SIRPGWFWHK 300 SESPKKLSQL LEIYYNSVGR NCLLLLNVPP NTTGLISETD VNRLREFRAA IDTIFSTNLA 360 HHQGCSTKAS SERGGKSGAF GADRVLDNDH LWTYWAPSGR ERKGEYWIEI KCGGGGLKNF 420 NVIRVQEAIG LGQRVKRHEV YVDGVRVAQG TTIGYKRLHR IGKGEPFSGE IVRVKVLESR 480 GVPLLSSIGI HYDPYWHP* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 6.0e-27 | 60 | 347 | 329 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 2.0e-29 | 83 | 347 | 284 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 6.0e-59 | 50 | 490 | 456 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 49 | 498 | 22 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 36 | 498 | 6 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 15 | 498 | 8 | 482 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 47 | 498 | 39 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 47 | 498 | 40 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 41 | 491 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 41 | 491 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3mo4_B | 0 | 46 | 486 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 46 | 486 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 46 | 486 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
