| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10033734 |
| Family | GT47 |
| Protein Properties | Length: 493 Molecular Weight: 55764.8 Isoelectric Point: 9.0244 |
| Chromosome | Chromosome/Scaffold: 701 Start: 1337212 End: 1339048 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 66 | 417 | 0 |
| NSIKVYVANLPRSLNYGLLERYWSSWGPDTRISNDPDHSPGKKNPVSLRGDTKFPPYPENPVIKQYSAEYWILGDLMTPENSRTNSFAKRVFDEREADVV FVPFFAALSTEMELARGKGTFRKKDGNEDYQRQKETLDFVMNTEAWKRSGGRDHVFVLTDPVAMWHVKAQIAPAVLLVVDFGGWHRLDSKSSNGSSSGKI QHTQVSLLKDVIVPYTHLLPQLSLSENSKRNTLLYFKGAKHRHGGGVVREKLWELLVNEPGVIMEEGFPNATGREQSIRGMRTSEFCLHPAGDTPTSCRL FDAIQSLCIPVIVSDSIELPFEGTVDYSEFSVFVAVSDALKPDWLVHHLRSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 493 Download |
| MAFILQILLM VGGYYKRTQL PCSIVSTFLA FIAISLLSLF YFNFYSASSS QKFITQSQTN 60 IHTPQNSIKV YVANLPRSLN YGLLERYWSS WGPDTRISND PDHSPGKKNP VSLRGDTKFP 120 PYPENPVIKQ YSAEYWILGD LMTPENSRTN SFAKRVFDER EADVVFVPFF AALSTEMELA 180 RGKGTFRKKD GNEDYQRQKE TLDFVMNTEA WKRSGGRDHV FVLTDPVAMW HVKAQIAPAV 240 LLVVDFGGWH RLDSKSSNGS SSGKIQHTQV SLLKDVIVPY THLLPQLSLS ENSKRNTLLY 300 FKGAKHRHGG GVVREKLWEL LVNEPGVIME EGFPNATGRE QSIRGMRTSE FCLHPAGDTP 360 TSCRLFDAIQ SLCIPVIVSD SIELPFEGTV DYSEFSVFVA VSDALKPDWL VHHLRSISER 420 EKERFRREMS MVQPVFQYEN GHPSGIGPVP PDGAVNYIWR KVHQKLPMIK EAIVREKRRP 480 PGVSVPLRCQ CT* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-59 | 64 | 417 | 366 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564443.1 | 0 | 62 | 491 | 51 | 476 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270238.1 | 0 | 22 | 492 | 17 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325567.1 | 0 | 22 | 492 | 13 | 476 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002327326.1 | 0 | 53 | 492 | 7 | 449 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533317.1 | 0 | 58 | 492 | 45 | 478 | catalytic, putative [Ricinus communis] |
