| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10034951 |
| Family | GT47 |
| Protein Properties | Length: 674 Molecular Weight: 76638.6 Isoelectric Point: 7.741 |
| Chromosome | Chromosome/Scaffold: 29 Start: 626952 End: 629820 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 343 | 624 | 0 |
| ERTLKVYIYTDGKKPIFHVPILKGLYASEGWFMKLMQGSKQFVVKDPQKAHLFYMPFSSRMLEYSLYVRNSHNRTNLRQHLNEYTEKIAAKYPYWNRTGG ADHFLVACHDWAPYETRQHMDHCIKALCNADVTVGFKLGTDVSLAETFIRAARNPLRGLGGKPPSQRHILAFYAGGMHGYLRPILVEQWKDKEPDMKIFG PMPGSSKMNYIQHMKSSKYCICPKGFEVNSPRVVESIFYECVPVIISDNFVPPLFEVFDWKAFSVILPEKDIPNLKRILVSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 674 Download |
| MFMQPSQVSS VDQWNLNMEF HLRLPKFNQI ESKKWLIFLV AVAIAHLLFQ PLLFPYGYNI 60 RSLLPTANDS MFDQSGMIAT AAEQSSVKPG TSRNALAVDA STSTSSLKID FISRNDNKSD 120 GAGDRSHVSE AKGHDQDTDE EEEEDLDDGP AELAVDRDVV DDDEVSLESS SILEFPSEAR 180 RDLPLYKNVT IKSSEEETNV SRAVPKSPSI VFEAPPVNYQ AVTRTTIDAP LEANESSSVF 240 PAVVKGASIV SRDKNGRVSS PVKKQTKTEM PPTTITTIDE MNDLLAHHGR SSLTMRPSSV 300 RDQEILAARA QIENAPLLVN DQDLYAPLFR NVSQFKRSYE LMERTLKVYI YTDGKKPIFH 360 VPILKGLYAS EGWFMKLMQG SKQFVVKDPQ KAHLFYMPFS SRMLEYSLYV RNSHNRTNLR 420 QHLNEYTEKI AAKYPYWNRT GGADHFLVAC HDWAPYETRQ HMDHCIKALC NADVTVGFKL 480 GTDVSLAETF IRAARNPLRG LGGKPPSQRH ILAFYAGGMH GYLRPILVEQ WKDKEPDMKI 540 FGPMPGSSKM NYIQHMKSSK YCICPKGFEV NSPRVVESIF YECVPVIISD NFVPPLFEVF 600 DWKAFSVILP EKDIPNLKRI LVSIPEKRYV DLQLAVRKVQ KHFLWHARPV KFDLFHMTLH 660 SIWYNRVYQM KLR* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 7.0e-63 | 342 | 624 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 16 | 669 | 708 | 1390 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 26 | 671 | 9 | 711 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_197468.1 | 0 | 92 | 673 | 64 | 600 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002283936.1 | 0 | 270 | 673 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514248.1 | 0 | 18 | 673 | 1 | 676 | catalytic, putative [Ricinus communis] |
