Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10036219 |
Family | GT47 |
Protein Properties | Length: 568 Molecular Weight: 63398.6 Isoelectric Point: 7.4717 |
Chromosome | Chromosome/Scaffold: 27 Start: 217574 End: 219773 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 178 | 491 | 0 |
KRVKVFMYDLPREFTFGIIDGRTTDGHARARGSSDLSQVRYPGHQHMGEWYLFADLNRTEEERVGSPVLRVYDPDEAELFYVPVFSSLSLIVNTNRPGAP DSGYSDEKMQDELVQWLEQQEYWRRNNGRDHVIVAGDPNALYRVLDRVKNSVLLLSDFGRVRSDQGSLVKDLIVPYAHRINSYTGEIGVGNRNTLLFFMG NRYRKDGGRIRDLFFQMLETENDVIIKHGTQSRENRRAATRGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKIAIFVGTKA SLQPGYLVNLLKGV |
Full Sequence |
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Protein Sequence Length: 568 Download |
MCISKSEINS PLSFISIIIP LCTSILAGLR KGYEAYQNDV AVATHASRAR YKPVPDPPGQ 60 EKGSTTVATS YATTSSAISM EELEAPSSPS KSKSPNNNIF QQITSSSSSS SSSSSNPHSS 120 SSMARKSYFV RQTIICSACF VFALYAVFNT FLNPATPAPP LFPDGVVRTE AFSVDEDKRV 180 KVFMYDLPRE FTFGIIDGRT TDGHARARGS SDLSQVRYPG HQHMGEWYLF ADLNRTEEER 240 VGSPVLRVYD PDEAELFYVP VFSSLSLIVN TNRPGAPDSG YSDEKMQDEL VQWLEQQEYW 300 RRNNGRDHVI VAGDPNALYR VLDRVKNSVL LLSDFGRVRS DQGSLVKDLI VPYAHRINSY 360 TGEIGVGNRN TLLFFMGNRY RKDGGRIRDL FFQMLETEND VIIKHGTQSR ENRRAATRGM 420 HTSKFCLNPA GDTPSACRLF DSIVSLCVPV IVSDSIELPF EDVIDYRKIA IFVGTKASLQ 480 PGYLVNLLKG VSTERILEFQ KELKRVSHYF EYGEPNGAVN EIWRQVTQKL PLIKLMINRD 540 KRVINRDSNE PDCSCLCTNQ TGVVSSL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-75 | 178 | 491 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 123 | 567 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 179 | 567 | 59 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 184 | 567 | 1 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 123 | 567 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 123 | 567 | 1 | 452 | catalytic, putative [Ricinus communis] |