Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10037016 |
Family | GT47 |
Protein Properties | Length: 453 Molecular Weight: 52557.1 Isoelectric Point: 9.2433 |
Chromosome | Chromosome/Scaffold: 31 Start: 1649715 End: 1651893 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 386 | 0 |
PLNVYMYDLPRKFHVGMMDPAAGQENEPVTVENIPRWQKNAGVRKQHSVEYWLMVSLLSDGDGGGGREAVRVLDPEKADAFYVPFFSSLSFNTHGHNMTD PETEADRQLQVEIIDMLYKSKYWQRSGGRDHVIPMTHPNAFRFLRQELNASILIVVDFGRYPRSMSTLHKDVVAPYVHVVDTFTNDDVKDPYESRKTLIF FRGSTVRKDEGKVRAKLEKILAGQENVRYEQGRPTTHSIQESTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVVVSDKIELPYEDEIDYTKFALFFS DSKALKPGYLVDKLRN |
Full Sequence |
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Protein Sequence Length: 453 Download |
MEEIGRTRSH KMYGKVIISV IFFLLLAFLY SIFIGSLDFR PYFFPRLPQL QQQHSPEASP 60 PADASSCEYK PLNVYMYDLP RKFHVGMMDP AAGQENEPVT VENIPRWQKN AGVRKQHSVE 120 YWLMVSLLSD GDGGGGREAV RVLDPEKADA FYVPFFSSLS FNTHGHNMTD PETEADRQLQ 180 VEIIDMLYKS KYWQRSGGRD HVIPMTHPNA FRFLRQELNA SILIVVDFGR YPRSMSTLHK 240 DVVAPYVHVV DTFTNDDVKD PYESRKTLIF FRGSTVRKDE GKVRAKLEKI LAGQENVRYE 300 QGRPTTHSIQ ESTEGMRSSK FCLHPAGDTP SSCRLFDAIV SHCVPVVVSD KIELPYEDEI 360 DYTKFALFFS DSKALKPGYL VDKLRNFPKK RWLEMWRNLK NISRHFEFEF PPTKGDATDM 420 LWRQIRRKLP EAQLAVHRSH RLTVPDWWRR RR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-65 | 70 | 387 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 12 | 429 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 12 | 448 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 71 | 452 | 52 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 71 | 448 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 12 | 451 | 1 | 434 | catalytic, putative [Ricinus communis] |