Basic Information | |
---|---|
Species | Linum usitatissimum |
Cazyme ID | Lus10038355 |
Family | GT47 |
Protein Properties | Length: 441 Molecular Weight: 50145.1 Isoelectric Point: 7.4952 |
Chromosome | Chromosome/Scaffold: 28 Start: 874937 End: 876817 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 56 | 364 | 0 |
KRVKVFMYDLPREFTFGIIDGHARARGSSDLSQVRYPGHQHMGEWYLFADLNRTEEERVGSPVIRVYDPDEAELFYVPVFSSLSLIVNTNRPGAPDPGYS DERMQDELVQWLEQKEYWRRNSGRDHVIVAGDPNALYRVLDHVKNSVLLLSDFGRVRSDQGSLVKDLIVPYAHRINSYTGEIGVGNRNTLLFFMGNRYRK DGGRIRDLFFQMLETENDVIIKHGTQSRENRRAATRGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKIAIFVGTKASLKPG YLVNLLKGV |
Full Sequence |
---|
Protein Sequence Length: 441 Download |
MARKSYFVRQ TIICSACFVF ALYAVFNTFL NPATPAPPLF PDGVVRTEAF SVDEDKRVKV 60 FMYDLPREFT FGIIDGHARA RGSSDLSQVR YPGHQHMGEW YLFADLNRTE EERVGSPVIR 120 VYDPDEAELF YVPVFSSLSL IVNTNRPGAP DPGYSDERMQ DELVQWLEQK EYWRRNSGRD 180 HVIVAGDPNA LYRVLDHVKN SVLLLSDFGR VRSDQGSLVK DLIVPYAHRI NSYTGEIGVG 240 NRNTLLFFMG NRYRKDGGRI RDLFFQMLET ENDVIIKHGT QSRENRRAAT RGMHTSKFCL 300 NPAGDTPSAC RLFDSIVSLC VPVIVSDSIE LPFEDVIDYR KIAIFVGTKA SLKPGYLVNL 360 LKGVSTERIL EFQKELKRVS HYFEYGEPNG AVNEIWRQVT QKLPLIKLMI NRDKRVINRD 420 SNEPDCSCLC TNQTGIVSSL * |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-76 | 56 | 364 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 1 | 440 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 57 | 440 | 59 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 62 | 440 | 1 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 1 | 440 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 1 | 440 | 1 | 452 | catalytic, putative [Ricinus communis] |