Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10039142 |
Family | GT47 |
Protein Properties | Length: 556 Molecular Weight: 62387.7 Isoelectric Point: 9.1834 |
Chromosome | Chromosome/Scaffold: 34 Start: 1844602 End: 1847698 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 216 | 498 | 0 |
EKQFKVFVYEEGEPPLFHNGPCKSIYAMEGNFIHGMEIDPKFRTKDPDKAHMFFLPFSVAMLVQFVYVRDSHDFGPIRRTVADYVELVAKKYPYWNRSLG ADHFMLACHDWGPEASFSVPFLGKNSIRALCNANTSERFNPVKDVSFPEINLRTGTTRGFIGGPSPSKRSILAFFAGGLHGPIRPILLQHWEKKNDEDVR VHQYLPKGISYYDMMRKSKFCLCPSGYEVASPRVVEAIYAGCVPVLISDHYVPPFSDVLNWKSFSVEVPVSEIPSLKTILEGI |
Full Sequence |
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Protein Sequence Length: 556 Download |
MRNDKVKKLC GSACRMCSSS SNSVKLLWVF VLLILVYGLV SNFGPTLSGL DLLASNGTDT 60 SKAGMVMVGG GRVESVEEKK MAVSADELSL VHRSSSPPVS VHQQKEQPQP PVIDSQDEGS 120 NLDLLTTSKN QSSASNPVPN SASVSINETQ DLALEKKQIK KEITSLDKVE AGLQKARLAI 180 KQSKIGNQTL DDPQYVPTGP MYWNARAFHA SYREMEKQFK VFVYEEGEPP LFHNGPCKSI 240 YAMEGNFIHG MEIDPKFRTK DPDKAHMFFL PFSVAMLVQF VYVRDSHDFG PIRRTVADYV 300 ELVAKKYPYW NRSLGADHFM LACHDWGPEA SFSVPFLGKN SIRALCNANT SERFNPVKDV 360 SFPEINLRTG TTRGFIGGPS PSKRSILAFF AGGLHGPIRP ILLQHWEKKN DEDVRVHQYL 420 PKGISYYDMM RKSKFCLCPS GYEVASPRVV EAIYAGCVPV LISDHYVPPF SDVLNWKSFS 480 VEVPVSEIPS LKTILEGISP RQYIRMQRRV LQVRRHFEVN SPARRYDVFH MILHSIWLRR 540 LNVRIHGDQL ATITS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-71 | 215 | 498 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 140 | 545 | 3 | 405 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 140 | 545 | 113 | 515 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 215 | 546 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 215 | 543 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 76 | 555 | 100 | 574 | catalytic, putative [Ricinus communis] |