| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10039598 |
| Family | GH89 |
| Protein Properties | Length: 816 Molecular Weight: 92561.6 Isoelectric Point: 6.2457 |
| Chromosome | Chromosome/Scaffold: 15 Start: 680017 End: 685000 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 109 | 812 | 0 |
| AEIIIKGTTAVEIVSGLHWYIKYWCGAHVSWDKTGGIQIASIPKPGSLPRVKKGGIIIQRPVPWNYYQNVVTSSYSYVWWNWERWEKEIDWMALQGINLP LAFNGQEAIWQKVFMKFNISAHDLDGFFGGPAFLAWARMGNLHGWGGPLSQSWLDGQLTLQKQILARMLELGMTPVLPSFSGNVPAALSKVFPSAKITRL GDWNTVNKNPRWCCTYLLDPSDPLFVEMGRAFIKQQIEEYGDVTDIYNCDTFNENSPPTDDPEYITSLGAAVYKAMSAGDQNAVWLMQGWLFYSDFVFWQ PPQVKALLHSVPFGKMIVLDLFAESKPIWESSSQFYDTPYVWCMLHNFGGNLEMYGMLDSIASGPVDARVSENSTMVGVGLCMEGIEHNPVVYELMSEMT FREEKVHVLEWLKTYALRRYGKAVPQIDEAWDILYHTIYNCTDGVADHNTDFIVKLPDWDPSLHSDNSKQDKIHTLHIGGRFLFQLQSSDLPEAHIWYSN QDTVKALQLFLGAGDKLNGSLTYRYDLVDLTRQVLSKLANEVYTKAILAFRNKDVSSLKHYSKKFLELIKDIDVLLASDDNFLLGTWLESAKALADNPID SKLNEWNARTQVTMWYDTTEAIQSKLHDYANKFWSGLLEDYYLPRAATYFDHLIRTLEKNEEFSLVDWRVKWIGLSNKWQTGSNLYPVKAEGDALSISRS LYEK | |||
| Full Sequence |
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| Protein Sequence Length: 816 Download |
| MKMGKPTMSN LNSLLSFTTL AVTWILLFHS QVGLAMSGGR RDAIESLVSR LDSRKSSSSV 60 QESAARGVLI RLFPAYQNSF DFKIVSKESC SGKSCFLIGN QAKPNLNGAE IIIKGTTAVE 120 IVSGLHWYIK YWCGAHVSWD KTGGIQIASI PKPGSLPRVK KGGIIIQRPV PWNYYQNVVT 180 SSYSYVWWNW ERWEKEIDWM ALQGINLPLA FNGQEAIWQK VFMKFNISAH DLDGFFGGPA 240 FLAWARMGNL HGWGGPLSQS WLDGQLTLQK QILARMLELG MTPVLPSFSG NVPAALSKVF 300 PSAKITRLGD WNTVNKNPRW CCTYLLDPSD PLFVEMGRAF IKQQIEEYGD VTDIYNCDTF 360 NENSPPTDDP EYITSLGAAV YKAMSAGDQN AVWLMQGWLF YSDFVFWQPP QVKALLHSVP 420 FGKMIVLDLF AESKPIWESS SQFYDTPYVW CMLHNFGGNL EMYGMLDSIA SGPVDARVSE 480 NSTMVGVGLC MEGIEHNPVV YELMSEMTFR EEKVHVLEWL KTYALRRYGK AVPQIDEAWD 540 ILYHTIYNCT DGVADHNTDF IVKLPDWDPS LHSDNSKQDK IHTLHIGGRF LFQLQSSDLP 600 EAHIWYSNQD TVKALQLFLG AGDKLNGSLT YRYDLVDLTR QVLSKLANEV YTKAILAFRN 660 KDVSSLKHYS KKFLELIKDI DVLLASDDNF LLGTWLESAK ALADNPIDSK LNEWNARTQV 720 TMWYDTTEAI QSKLHDYANK FWSGLLEDYY LPRAATYFDH LIRTLEKNEE FSLVDWRVKW 780 IGLSNKWQTG SNLYPVKAEG DALSISRSLY EKYFS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12971 | NAGLU_N | 3.0e-21 | 61 | 159 | 99 | + Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold. | ||
| pfam12972 | NAGLU_C | 1.0e-106 | 518 | 813 | 296 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| pfam05089 | NAGLU | 0 | 174 | 513 | 340 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24942.1 | 0 | 1 | 815 | 48 | 868 | unnamed protein product [Vitis vinifera] |
| GenBank | EEE59081.1 | 0 | 56 | 815 | 51 | 812 | hypothetical protein OsJ_10898 [Oryza sativa Japonica Group] |
| RefSeq | NP_196873.1 | 0 | 28 | 814 | 16 | 805 | alpha-N-acetylglucosaminidase family / NAGLU family [Arabidopsis thaliana] |
| RefSeq | XP_002273084.1 | 0 | 24 | 815 | 7 | 803 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314048.1 | 0 | 40 | 814 | 25 | 805 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 76 | 803 | 186 | 866 | A Chain A, Family Gh5 Endo-Beta-Mannanase From Lycopersicon Esculentum (Tomato) |
| PDB | 2vcb_A | 0 | 76 | 803 | 186 | 866 | A Chain A, Family Gh5 Endo-Beta-Mannanase From Lycopersicon Esculentum (Tomato) |
| PDB | 2vca_A | 0 | 76 | 803 | 186 | 866 | A Chain A, Family Gh5 Endo-Beta-Mannanase From Lycopersicon Esculentum (Tomato) |
| PDB | 2vc9_A | 0 | 76 | 803 | 186 | 866 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 76 | 803 | 209 | 889 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
