Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10039980 |
Family | GT47 |
Protein Properties | Length: 584 Molecular Weight: 66623.7 Isoelectric Point: 8.8817 |
Chromosome | Chromosome/Scaffold: 12 Start: 913589 End: 917237 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 132 | 418 | 0 |
KRFKIWTYKEGERPLVHRAPMSNIYSIEGQFLDEMESGISQFRANSPEEAHMFYLPFSVASIIHFIYQPILSKQDYNRDRLQRIVADYIDVVADKYPFWN RSQGADHFMVSCHDWAPDISTANPTLYSKFIRVLCNANTSEGFQPSRDASLPEIYLEYERLAPRNVGHDPINRTILAFFAGRAHGYIRRMLFEHWKDKDD NQVQVFTKLPSREIYTSKIGRSKFCLCPSGYEVASPRIVEAINQGCIPVLISMNYSLPFREVLDWDKFTVGIPVERIGDIKKVLEGI |
Full Sequence |
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Protein Sequence Length: 584 Download |
MGEQSYSGSR PIYSAIPIFL LLLLLLFTVS PITDNHYFSN LFAYFGSSNG DYRDVDVGRS 60 FKTQKMINGS NNGSSSSSVE IIEEDLSRAR AAIREAVRTQ SYTSYKEEPF IPRGPVYRSP 120 YAFQQSHIEM VKRFKIWTYK EGERPLVHRA PMSNIYSIEG QFLDEMESGI SQFRANSPEE 180 AHMFYLPFSV ASIIHFIYQP ILSKQDYNRD RLQRIVADYI DVVADKYPFW NRSQGADHFM 240 VSCHDWAPDI STANPTLYSK FIRVLCNANT SEGFQPSRDA SLPEIYLEYE RLAPRNVGHD 300 PINRTILAFF AGRAHGYIRR MLFEHWKDKD DNQVQVFTKL PSREIYTSKI GRSKFCLCPS 360 GYEVASPRIV EAINQGCIPV LISMNYSLPF REVLDWDKFT VGIPVERIGD IKKVLEGISE 420 ERYLEMYHRV RSVGRHFLIN RPAKPYDLLH MILHSLWLRS CHSFLATFSR RTLSHNPNCH 480 CNHSSVTMAI LQSHSVASTR PSIVPHSSAP LAEPRFPPGP IPPITPAPTP QGMTPPQHHD 540 NPKKIPTVSV DGEPQDRNDG NHHPGGRSPF VRRYRRPNPS LGI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-56 | 130 | 418 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 45 | 459 | 212 | 607 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 77 | 459 | 13 | 394 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25529.1 | 0 | 77 | 459 | 2 | 380 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 77 | 459 | 86 | 469 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 76 | 459 | 4 | 388 | PREDICTED: hypothetical protein [Vitis vinifera] |