Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10043238 |
Family | GT47 |
Protein Properties | Length: 523 Molecular Weight: 59825.4 Isoelectric Point: 10.3026 |
Chromosome | Chromosome/Scaffold: 25 Start: 1949570 End: 1951858 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 186 | 473 | 0 |
RTMKVYIYKEGEKPVFHRSRMRGIYASEGWFMKLIKESKRFVVKDPRKAHLFYIPFSSEMLRKELYGSPTLHTVKDLEQHLQGYVNLVSQKYMFWNRSNG ADHFVVGCHDWAPKLTSNPMRRCIRVLCNANVGKGFRIGKDTTLPVTSIRSQERPTQDIGGKPPSERHILAFFAGGSHGSLRPVLLQHWAADNNGPHQTM KILGPMPRDVESKRLYRDYMKSSKYCICARGHEVHTPRVVEAIYYECVPVIISDNYVPPFFEVLNWEEFAVFVLEKDVPKLKEILSAI |
Full Sequence |
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Protein Sequence Length: 523 Download |
MAFAVWIRRS NVGSIIWRLL VIMAMAVIAL VLILVQLSSS PFANGRNGTP WSPLVARENF 60 SWVIIPANNP VVSDDSKLGE IQHRNDSSSS PSSKIVENVG GEIESTSKNR KVASVSAGKR 120 VGRKNPTTIS QMNSQILHSL FSATSMLRSA RMQIENVPIL KWDPGLHASS FWNVSSFMRS 180 YKLMERTMKV YIYKEGEKPV FHRSRMRGIY ASEGWFMKLI KESKRFVVKD PRKAHLFYIP 240 FSSEMLRKEL YGSPTLHTVK DLEQHLQGYV NLVSQKYMFW NRSNGADHFV VGCHDWAPKL 300 TSNPMRRCIR VLCNANVGKG FRIGKDTTLP VTSIRSQERP TQDIGGKPPS ERHILAFFAG 360 GSHGSLRPVL LQHWAADNNG PHQTMKILGP MPRDVESKRL YRDYMKSSKY CICARGHEVH 420 TPRVVEAIYY ECVPVIISDN YVPPFFEVLN WEEFAVFVLE KDVPKLKEIL SAIPEEKYLA 480 MQSSVKMVQQ HFLWHRKPLK YDLFHMILYS VWHNRVFEVK AL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-64 | 184 | 473 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 72 | 521 | 213 | 712 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 72 | 520 | 213 | 663 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 72 | 520 | 211 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324437.1 | 0 | 184 | 521 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514249.1 | 0 | 184 | 520 | 1 | 332 | catalytic, putative [Ricinus communis] |