Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10043239 |
Family | GT47 |
Protein Properties | Length: 610 Molecular Weight: 70477.2 Isoelectric Point: 9.2986 |
Chromosome | Chromosome/Scaffold: 25 Start: 1953017 End: 1955395 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 277 | 560 | 0 |
ERTLKVYVYKDGNKPIFHLPILKGLYASEGWFMKLMEGSKRFLVKDPRKAHLFYMPFSSRMLEYTLYVRNSHNRTNLRQYLKEYADLIAAKYPYWNRTGG ADHFLVACHDWAPYETRHHMEHCPKALCNADVTTGFKIGRDVSLPETYVRAATNPLRDLGGKPPSERHILAFYAGSMHGYLRQILIKHWKDKDPDMKIWG RMPLGVASKMNYISHMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVFDWSAFSIILAEKDIPNLKEILLSV |
Full Sequence |
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Protein Sequence Length: 610 Download |
MGFQFRLPNV YQIDARKWLI LLGTAVIAQA VFHILVISYG YTIWPLLPTS QDSMFDQTVM 60 TSRVESSINP GRMDGNALPL DASSSYGNLQ IRVLVRNDEK FDIEDSGVTS EVNVHHNDDD 120 DHGEVAVDRD VVVDDDDDND VRVDGNAVTR ERDSVMELLS EPKKDISTMK KIKEETSVRI 180 LVSGNTSAGV SIHAKKKMRC EMPPKSVTTF DEMNHLLARR RRSSRAMRPR WSSARDKEIL 240 AMKSQIENAA VLVKDPDLYA PLFRNVSQFK RSYELMERTL KVYVYKDGNK PIFHLPILKG 300 LYASEGWFMK LMEGSKRFLV KDPRKAHLFY MPFSSRMLEY TLYVRNSHNR TNLRQYLKEY 360 ADLIAAKYPY WNRTGGADHF LVACHDWAPY ETRHHMEHCP KALCNADVTT GFKIGRDVSL 420 PETYVRAATN PLRDLGGKPP SERHILAFYA GSMHGYLRQI LIKHWKDKDP DMKIWGRMPL 480 GVASKMNYIS HMKSSKYCIC PKGYEVNSPR VVESIFYECV PVIISDNFVP PFFEVFDWSA 540 FSIILAEKDI PNLKEILLSV PEKRYIELQL GVRKVQRHFL WHAKPVKYDL FLMTLHSIWY 600 NRVYQIKPR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-67 | 276 | 560 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 13 | 605 | 722 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 138 | 607 | 208 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 198 | 609 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 202 | 609 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 1 | 609 | 1 | 676 | catalytic, putative [Ricinus communis] |