Basic Information | |
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Species | Picea abies |
Cazyme ID | MA_10427831g0010 |
Family | GT47 |
Protein Properties | Length: 430 Molecular Weight: 48991 Isoelectric Point: 6.3941 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 63 | 395 | 0 |
VKIFMYDLPRKFTYGVIEHYQRARGVLKADGCPRRRGYPGQATGSDTDQLRYPGNQHSAEWWLFSHLSSMDDEEEMTNSSVIRTLDPHHADLFYVSFFSS LSLVVNPPGRHTMRNEESSSSYYSDEEIQEELVLWLEKQPYWRRYRGRDHVIICQDPNALYKVIDNFKNSVLLISDFGRLKAQQASLVKDVVLPYSHRIN SFNGDAGVGHRDSLLFFMGNRFRKEGGRVRDMLFQVLEDEEDIIIKHGTQSRESRRLATQGMHTSKFCLHPAGDTPSACRLFDAIVSLCVPVIVSDDIEL PFEDIIDYSKIAIFVTSSDAVQPGYLASMLRSV |
Full Sequence |
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Protein Sequence Length: 430 Download |
MGGRRSNLGY TLFMLVFACL LLYTAMNTFS LLFSPHLPEP PQHLVAPDDV ATPARPPAPT 60 PIVKIFMYDL PRKFTYGVIE HYQRARGVLK ADGCPRRRGY PGQATGSDTD QLRYPGNQHS 120 AEWWLFSHLS SMDDEEEMTN SSVIRTLDPH HADLFYVSFF SSLSLVVNPP GRHTMRNEES 180 SSSYYSDEEI QEELVLWLEK QPYWRRYRGR DHVIICQDPN ALYKVIDNFK NSVLLISDFG 240 RLKAQQASLV KDVVLPYSHR INSFNGDAGV GHRDSLLFFM GNRFRKEGGR VRDMLFQVLE 300 DEEDIIIKHG TQSRESRRLA TQGMHTSKFC LHPAGDTPSA CRLFDAIVSL CVPVIVSDDI 360 ELPFEDIIDY SKIAIFVTSS DAVQPGYLAS MLRSVSLERL LQYQIELVKV TILLDTYFIL 420 PSLLVDINLK |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-55 | 63 | 395 | 344 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC55656.1 | 0 | 56 | 410 | 53 | 393 | exostosin family protein-like protein [Oryza sativa Japonica Group] |
EMBL | CAN68074.1 | 0 | 63 | 411 | 72 | 401 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_001060019.1 | 0 | 56 | 410 | 100 | 440 | Os07g0567000 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002276440.1 | 0 | 63 | 411 | 105 | 434 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002460871.1 | 0 | 44 | 410 | 88 | 438 | hypothetical protein SORBIDRAFT_02g036640 [Sorghum bicolor] |