Basic Information | |
---|---|
Species | Picea abies |
Cazyme ID | MA_10428894g0010 |
Family | GT47 |
Protein Properties | Length: 481 Molecular Weight: 54452.5 Isoelectric Point: 7.0118 |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 55 | 406 | 0 |
HESLRVYIADLPREMNYGLLEDYWSQKDRRAAEDADEELRAAVLAGMEYPPYALNPLIRQYSAEYWLLGDLLTPPELRGKMDTSSVAKRVWKVEDADVVF VPFFATLSAEMQLDRAKGKFRHKKDDNEDYRRQMKVVDLIKSSAAWQRSGGRDHVFVLTDPVAMWHVRAEIASAVLLVVDFGGWYMEDSNAHDAEGGAMI QHTQISLLKDVILPYTHLLPMLHISNDRPRETLLYFKGARHRHRGGLVRDKLWGLLQNEPGVVIEEGFPNSTGREQSIQGMRNAEFCLHPAGDTPTSCRL FDAIVSLCIPVIVSDNIELPFEGMIEYTEFSVFVSVQDALQPNWLVKHLNGI |
Full Sequence |
---|
Protein Sequence Length: 481 Download |
MAQRGLFLPC SVAILIFVAG LLCIFYISSP FTSTTTTTTN FEHCGSSSFS SHSVHESLRV 60 YIADLPREMN YGLLEDYWSQ KDRRAAEDAD EELRAAVLAG MEYPPYALNP LIRQYSAEYW 120 LLGDLLTPPE LRGKMDTSSV AKRVWKVEDA DVVFVPFFAT LSAEMQLDRA KGKFRHKKDD 180 NEDYRRQMKV VDLIKSSAAW QRSGGRDHVF VLTDPVAMWH VRAEIASAVL LVVDFGGWYM 240 EDSNAHDAEG GAMIQHTQIS LLKDVILPYT HLLPMLHISN DRPRETLLYF KGARHRHRGG 300 LVRDKLWGLL QNEPGVVIEE GFPNSTGREQ SIQGMRNAEF CLHPAGDTPT SCRLFDAIVS 360 LCIPVIVSDN IELPFEGMIE YTEFSVFVSV QDALQPNWLV KHLNGISKMQ RSIMRRSMAQ 420 VQHIFEYDNG YPGGIGPPVK DGAVNHIWKK IMHKVPTIKE MVVRERRKPN GTSIPLRCHC 480 T |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-58 | 58 | 406 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAE02830.1 | 0 | 58 | 481 | 46 | 464 | OSJNBa0043A12.35 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_564443.1 | 0 | 48 | 480 | 47 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002325567.1 | 0 | 52 | 481 | 50 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 22 | 481 | 3 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 56 | 481 | 53 | 478 | catalytic, putative [Ricinus communis] |